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Nicotine and Other Insecticidal Alkaloids

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Nicotinoid Insecticides and the Nicotinic Acetylcholine Receptor

Abstract

Alkaloids, with more than 10,000 described, are one of the most diverse and prominent groups of natural products with pharmacological and toxicological importance (Harborne 1993). Plant extracts containing insecticidal alkaloids as bioactive constituents have played an important role in the abatement of insects of agricultural and public health importance for centuries. While the direct use of these substances has recently diminished, they continue to serve as leads for synthetic analogs and are also indispensable biochemical tools in mode of action studies. In recent years, the function of these alkaloids in the host plant has begun to unfold: it is now generally believed that the ecological role of these compounds, often acting in concert with other nonalkaloidal substances, is to provide a chemical defense against predators and pathogens in a sustained manner through multiple biological mechanisms (Wink 1993a; Brown and Trigo 1995).

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Authors and Affiliations

  1. Hungarian Academy of Sciences, Plant Protection Institute, Herman Ottó út 15, H-1022, Budapest, Hungary

    István Ujváry

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  1. István Ujváry
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Editors and Affiliations

  1. Tokyo University of Agriculture, 1-1 Sakuragaoka 1, Setagaya-ku, Tokyo, 156-8502, Japan

    Izuru Yamamoto (Professor Emeritus) (Professor Emeritus)

  2. University of California, Berkeley, California, 94720-3112, USA

    John E. Casida (Professor of Entomology and Director of Environmental Chemistry and Toxicology Laboratory) (Professor of Entomology and Director of Environmental Chemistry and Toxicology Laboratory)

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© 1999 Springer Japan

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Ujváry, I. (1999). Nicotine and Other Insecticidal Alkaloids. In: Yamamoto, I., Casida, J.E. (eds) Nicotinoid Insecticides and the Nicotinic Acetylcholine Receptor. Springer, Tokyo. https://doi.org/10.1007/978-4-431-67933-2_2

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  • DOI: https://doi.org/10.1007/978-4-431-67933-2_2

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68011-6

  • Online ISBN: 978-4-431-67933-2

  • eBook Packages: Springer Book Archive

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