Intratumoral Angiogenesis and Micrometastasis in Bone Marrow of Patients with Gastric Cancer

  • Yoshihiro Kakeji
  • Yoshihiko Maehara
  • Kotaro Shibahara
  • Shota Hasuda
  • Eriko Tokunaga
  • Eiji Oki
  • Keizo Sugimachi


Detection of metastasis in early stages is difficult, as small numbers of tumor cells are not readily visible against a background of host cells. Often identification of metastases is made only during follow-up investigations, and by that time a solid tumor mass has already formed. The visualization of tumor invasion and micro-metastasis formation are needed for a better understanding of tumor progression and its control, all of which will improve the survival time for such patients.


Gastric Cancer Vascular Endothelial Growth Factor Early Gastric Cancer Advanced Gastric Cancer Vascular Endothelial Growth Factor Expression 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Japan 1999

Authors and Affiliations

  • Yoshihiro Kakeji
    • 1
  • Yoshihiko Maehara
    • 1
  • Kotaro Shibahara
    • 1
  • Shota Hasuda
    • 1
  • Eriko Tokunaga
    • 1
  • Eiji Oki
    • 1
  • Keizo Sugimachi
    • 1
  1. 1.Department of Surgery II, Faculty of MedicineKyushu UniversityFukuokaJapan

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