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A Modeling System of 3-Dimensional Blood Vessel Configuration for CFD Analysis

  • Makoto Misawa
  • Yusuke Kimura
  • Hao Liu
  • Takami Yamaguchi

Abstract

Atherosclerosis develops on specific parts of vessel walls, and this observation is why we relate atherosclerosis to blood flow. Among these specific locations, the bifurcations of blood vessels are especially prone to atherosclerosis, particularly the lateral walls of the common iliac arteries. This distribution of lesions is believed to depend on fluid dynamics phenomena. Since the flow in an arterial bifurcation is too complex to study in vivo, or even with in vitro experiments, we have been conducting studies using computational fluid dynamics (CFD). In order to study the relationship between the blood flow in the bifurcation of a blood vessel and atherosclerosis using CFD, good CFD models must be constructed. A bifurcation has a complex three-dimensional (3-D) configuration, particularly the sharp edge, and therefore minute deformation and relative displacement of the bifurcation are thought to have a significant effect on blood flow. In this study, we applied the technique used in histology of slicing vessels embedded in paraffin into micrometer thicknesses to develop a modeling system. A computer captured two-dimensional images of the face of each slice and then used serial images to reconstruct the 3-dimensional blood vessel configuration with the precision required for CFD analysis.

Keywords

Computational Fluid Dynamic Common Iliac Artery Aortic Bifurcation Computational Fluid Dynamic Analysis Micrometer Thickness 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Yamaguchi T, Hanai S, Oyama T, Mitsumata M, Yoshida Y(1986) Effect of blood flow on the localization of fibrocelluar intima thickening and atherosclerosis at the young human abdominal aorta-inferior mesenteric artery branching (in Japanese). Advances in Cardiovascular Research 7: 97–108Google Scholar

Copyright information

© Springer Japan 2000

Authors and Affiliations

  • Makoto Misawa
    • 1
  • Yusuke Kimura
    • 1
  • Hao Liu
    • 1
  • Takami Yamaguchi
    • 1
  1. 1.Department of Mechanical and Systems EngineeringNagoya Institute of TechnologyNagoyaJapan

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