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Computational Analysis and Visualization of Spiral Wave Reentry in a Virtual Heart Model

  • Kazuo Nakazawa
  • Tohru Suzuki
  • Takashi Ashihara
  • Masashi Inagaki
  • Tsunetoyo Namba
  • Takanori Ikeda
  • Ryoji Suzuki

Summary

It has been suggested that spiral wave reentry is the principal mechanism of functional tachyarrhythmias. In this study, we present images of the dynamics of tachyarrhythmic excitation propagation based on spiral wave reentry obtained in a virtual heart model. For this purpose, we employed high-performance computation techniques using a supercomputer and visualizing techniques using color computer graphics. In this heart model, the myocardial units were represented by two types of non-linear ordinary differential equations. The myocardial units were connected to each other into simple shaped two-or three-dimensional media corresponding to the heart walls and also into a human ventricular-shaped medium. The dynamics of excitation propagation were visualized intelligibly through various improvements in the visualizing techniques employed in the implementation of the three-dimensional graphics. Our results suggested that it is possible for lethal arrhythmia, commonly called ventricular fibrillation, to occur even in hearts without any conduction abnormalities or repolarization heterogeneity, e.g., infarction or ischemia, and cause sudden death.

Keywords

Conduction Velocity Spiral Wave Excitation Propagation Ventricular Model Scroll Wave 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Japan 2000

Authors and Affiliations

  • Kazuo Nakazawa
    • 1
  • Tohru Suzuki
    • 1
  • Takashi Ashihara
    • 2
  • Masashi Inagaki
    • 3
  • Tsunetoyo Namba
    • 4
  • Takanori Ikeda
    • 5
  • Ryoji Suzuki
    • 6
  1. 1.Department of EpidemiologyNational Cardiovascular Center Research InstituteFujishiro-dai, SuitaJapan
  2. 2.First Department of Internal MedicineShiga University of Medical ScienceSeta Tsukinowacho, OtsuJapan
  3. 3.Department of Cardiovascular DynamicsNational Cardiovascular Center Research InstituteFujishiro-dai, SuitaJapan
  4. 4.Department of Cardiovascular MedicineOkayama University Medical SchoolShikata-cho, OkayamaJapan
  5. 5.Third Department of Internal Medicine, Ohashi HospitalToho UniversityOhashi, Meguro-ku, TokyoJapan
  6. 6.Human Information Systems LaboratoriesKanazawa Institute of TechnologyYatsukaho, MattoJapan

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