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Simulated Electrocardiogram of Spiral Wave Reentry in a Mathematical Ventricular Model

  • Takashi Ashihara
  • Tohru Suzuki
  • Tsunetoyo Namba
  • Masashi Inagaki
  • Takanori Ikeda
  • Makoto Ito
  • Masahiko Kinoshita
  • Kazuo Nakazawa

Summary

Spiral waves can be most commonly observed in structurally and electrophysiologically normal hearts during tachyarrhythmia, such as ventricular fibrillation. Electrocardiograms obtained during tachyarrhythmia can be very helpful in understanding the mechanism of this disease because the morphological variations they demonstrate can reflect the characteristics of spiral wave dynamics. A comparison of electrocardiograms obtained in computer simulations and those from actual clinical cases, showed that the important substrates of the mechanism of ventricular fibrillation are spiral wave meandering and breakup, resulting from the restitution property of action potential duration, wall thickness, twisted anisotropy, complex boundary, and so on. In some cases, the frequency spectrum of the electrocardiograms may prove useful in predicting the occurrence of spiral wave breakup and to understand the role of the substrate in the composition of the characteristic complex waveforms. In conclusion, the discrimination between ventricular tachycardia and ventricular fibrillation can be quite difficult due to the vague differences in the wave dynamics in the background.

Keywords

Ventricular Fibrillation Spiral Wave Fiber Rotation Fiber Twist Scroll Wave 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Japan 2000

Authors and Affiliations

  • Takashi Ashihara
    • 1
  • Tohru Suzuki
    • 2
  • Tsunetoyo Namba
    • 3
  • Masashi Inagaki
    • 4
  • Takanori Ikeda
    • 5
  • Makoto Ito
    • 1
  • Masahiko Kinoshita
    • 1
  • Kazuo Nakazawa
    • 2
  1. 1.First Department of Internal MedicineShiga University of Medical ScienceSeta Tsukinowa-cho, OtsuJapan
  2. 2.Department of EpidemiologyNational Cardiovascular Center Research InstituteFujishiro-dai, SuitaJapan
  3. 3.Department of Cardiovascular MedicineOkayama University Medical SchoolShikatacho, OkayamaJapan
  4. 4.Department of Cardiovascular DynamicsNational Cardiovascular Center Research InstituteFujishiro-dai, SuitaJapan
  5. 5.Third Department of Internal Medicine, Ohashi HospitalToho UniversityOhashi, Meguro-ku, TokyoJapan

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