α-Mannosidase II, also known as Golgi mannosidase II, mannosyl-oligosaccharide 1,3-1,6-α-mannosidase, 1,3-(1,6)mannosyl-oligosaccharide l,-D-mannohydrolase, and GlcNAc transferase I-dependent α1,3(α1,6)-mannosidase, is a glycosylhydrolase that catalyzes cleavage of the final two mannose residues during mammalian Asn- linked oligosaccharide processing and the removal of α1,3 and α1,6 mannose residues from GlcNAcMan5GlcNAc2-Asn to form GlcNAcMan3GlcNAc2-Asn. The enzyme is a member of glycosylhydrolase family 38.


Mannose Residue Glycosylhydrolase Family Golgi Stack Mung Bean Seedling Congenital Dyserythropoietic Anemia 
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Copyright information

© Springer Japan 2002

Authors and Affiliations

  • Kelley W. Moremen
    • 1
  1. 1.University of GeorgiaAthensUSA

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