ST3Gal-III is a CMP-N-acetylneuraminate: β-galactoside α2-3-sialyltransferase (Galβ1-3(4)GlcNAc α2-3-sialyltransferase). Like other sialyltransferases, ST3Gal-III exhibits type II membrane protein topology and has characteristic motifs for sialyltransferases which are called sialylmotifs L, S, and VS. ST3Gal-III also has a Kurosawa motif as seen in the ST3Gal family and two members of the ST6GalNAc family (Tsuji 1999).
KeywordsSialic Acid Acceptor Substrate Competitive Polymerase Chain Reaction Membrane Protein Topology Sialyltransferase Gene
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- Tsuji S (1999) Molecular cloning and characterization of sialyltransferases. In: Inoue Y, Lee YC, Troy FA (eds) Sialobiology and other novel forms of glycosylation. Gakushin, Osaka, pp 145–154Google Scholar