Histocytologic Criteria of Adenocarcinoma In Situ of the Esophagus

  • Carlos A. Rubio
Conference paper


Nearly 200 years ago Schmidt [1] reported the occurrence of aberrant foci of gastric mucosa in the esophagus. In 1897 Rüdinger [2] also referred to several publications on aberrant gastric mucosa in the esophagus in the American, English, and German literature; and about 60 years ago, in 1941, Rector and Connelly [3] found aberrant gastric mucosa in 11.8% (n=118) of 1000 esophaguses at autopsy. Thus, aberrant gastric mucosa and probably aberrant intestinal mucosa of the esophagus have been known for quite some time.


Esophageal Carcinoma Esophageal Adenocarcinoma Nuclear Polarity Lamina Propria Mucosa Intraepithelial Carcinoma 
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Copyright information

© Springer Japan 2002

Authors and Affiliations

  • Carlos A. Rubio
    • 1
  1. 1.Gastrointestinal and Liver Pathology Research LaboratoryKarolinska InstituteStockholmSweden

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