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Abstract

Replantation of amputated parts of the body by microvascular techniques has become a fairly common clinical procedure. To improve the success rate of this procedure, a considerable number of basic studies have been performed using experimental models of various animals [1–4].The rat hind limb amputation and replantation model has been especially widely used because rats are inexpensive and easy to handle, and because the diameter of their femoral vessels approximates that of the human finger and of various subcutaneous island flaps.

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References

  1. Buncke H.J., Schulz W.P. (1976) Experimental digital amputation and reimplantation. Plast Reconstr Surg 36:62

    Google Scholar 

  2. Buncke H.J., Schulz W.P. (1966) Total ear reimplantation in the rabbit utilizing microminiature vascular anastomoses. Br J Plast Surg 19:15–22

    Article  PubMed  Google Scholar 

  3. Hayhurst J.W. (1976) Complications of digital implantation. In: Daniller A.I., Strauch B. (eds) Symposium in microvascular surgery. CV, Mosby, St. Louis

    Google Scholar 

  4. Tsai T.M. (1975) Experimental and clinical application of microvascular surgery.Ann Surg 181:169–177

    Article  Google Scholar 

  5. Buncke H.J., Daniller A.I., Schulz W.P., Chase R.A. (1967) The fate of autogenous whole joints transplantated by microvascular anastomoses. Plast Reconstr Surg 39:333–341

    Article  PubMed  Google Scholar 

  6. Harashima T., Buncke H.J. (1975) Study of washout solutions for microvascular replantation and transplantation. Plast Reconstr Surg 56:542–548

    Article  Google Scholar 

  7. Shapiro R.I., Cerra F.B. (1977) A model for reimplantation and transplantation of a complex organ: The rat hind limb. J Surg Res 24:501–506

    Article  Google Scholar 

  8. Abramson D.L., Shaw W.W., Kamat B.R., Harper A., Rosenberg C.R. (1991) Laser-assisted venous anastomosis: A comparison study. J Reconstr Microsurg 7:199–203

    Article  PubMed  CAS  Google Scholar 

  9. Bass L.S., Treat M.R., Dzakonski C., Trokel S.L. (1989) Sutureless microvascular anastomosis using the THC:YAG laser: A preliminary report. Microsurgery 10:189–193

    Article  PubMed  CAS  Google Scholar 

  10. Han S.K., Kim S.W., Kim W.K. (1998) Microvascular anastomosis with minimal suture and fibrin glue: Experimental and clinical study. Microsurgery 18:306–311

    Article  PubMed  CAS  Google Scholar 

  11. Hyland W.T., Botens S.R., Minasi J.S. (1981) Are-appraisal and modification of the Lauritzen technique of microvascular anastomoses. Br J Plast Surg 34:451–453

    Article  PubMed  CAS  Google Scholar 

  12. Kiyoshige Y., Tsuchida H., Hamasaki M., Takayanagi M., Watanabe Y. (1991) CO2 laser assisted microvascular anastomosis: Biochemical studies and clinical applications. J Reconstr Microsurg 7:225–230

    Article  PubMed  CAS  Google Scholar 

  13. Lauritzen C. (1978) A new and easier way to anastomose microvessels. Scand J Plast Reconstr Surg 12:291–294

    Article  PubMed  CAS  Google Scholar 

  14. Ruiz-Razura A., Lan M., Cohen B.E. (1989) The laser assisted end to side microvascular anastomosis. Plast Reconstr Surg 83:511–517

    Article  PubMed  CAS  Google Scholar 

  15. Ruiz-Razura A., Wiener T.C. (1991) CO2 laser assisted microvascular anastomosis: Biochemical studies and clinical applications. Invited discussion. J Reconstr Microsurg 7:231–264

    Google Scholar 

  16. Sully L., Nightingale G., O’Brien B.Mc.C., Hurley J.V. (1982)The sleeve technique in microarterial anastomosis. Br J Plast Surg 34:451–453

    Google Scholar 

  17. Swartz W.M., Cha C.J.M., Ambler M., Clowes G.H.A. (1976) Prolonged ischemia in the replanted rat eg: A biochemical and morphologic study with microvascular techniques. Surg Forum 27:565–568

    PubMed  CAS  Google Scholar 

  18. Vale B.H., Frenkel A., Trenka-Benthin S., Matlaga B.F. (1986) Microsurgical anastomosis of rat carotid arteries with the CO2laser. Plast Reconstr Surg 77:759–766

    Article  PubMed  CAS  Google Scholar 

  19. Chait L.A., May J.W., O’Brien B.M., Hurley J.V. (1978) The effects of perfusion of various solutions on the no-reflow phenomenon in experimental free flaps. Plast Reconstr Surg 61:421–430

    Article  PubMed  CAS  Google Scholar 

  20. Gould I.S., Sully L., O’Brien B.M., Das S.F., Knight K.R., Hurley J.V. (1985) The effects of combined cooling and perfusion on experimental free-flap survival in rabbits. Plast Reconstr Surg 76:104–109

    Article  PubMed  CAS  Google Scholar 

  21. Rosen H.M., Slivjak M.J., McBrearty F.X. (1985)Preischemic flap washout and its effect on the no-reflow phenomenon. Plast Reconstr Surg 76:737–747

    PubMed  CAS  Google Scholar 

  22. Rosen H.M., Slivjak M.J., McBrearty F.X. (1987) Delayed micro circulatory hyperpermeability following perfusion washout. Preischemic flap washout. Plast Reconstr Surg 79:102–107

    Article  PubMed  CAS  Google Scholar 

  23. Rosen H.M., Slivjak M.J., McBrearty F.X. (1987) The role of perfusion washout in limb revascularization procedures. Plast Reconstr Surg 80:595–603

    Article  PubMed  CAS  Google Scholar 

  24. Im M.J., Shen W.H., Pak O. (1984) Effect of allopurinol on survival of hyperemic island skin flaps. Plast Reconstr Surg 73:276–278

    Article  PubMed  CAS  Google Scholar 

  25. Manson P.N., Narayan K.K., Im M.J. (1986) Improved survival in free skin flap transfers in rats. Surgery 99:211–215

    PubMed  CAS  Google Scholar 

  26. Sagi A., Ferder M., Levens D., Strauch B. (1986) Improved survival of island flaps after prolonged ischemia by perfusion with superoxide dismutase. Plast Reconstr Surg 77:639–644

    Article  PubMed  CAS  Google Scholar 

  27. Weiss A.P.C., Moore J.R., Randolph M.A., Weiland A.J. (1988) Preventing oxygen free-radical injury in ischemic revascularized bone grafts. Plast Reconstr Surg 82:486–497

    Article  PubMed  CAS  Google Scholar 

  28. Weiss A.P.C., Carey L.A., Randolph M.A., Moore J.R., Weiland A.J. (1989) Oxygen radical scavengers improve vascular patency and bone-muscle cell survival in an ischemic extremity replant model. Plast Reconstr Surg 84:117–123

    Article  PubMed  CAS  Google Scholar 

  29. Yokoyama K., Homan M., Takagishi K., Sekiguchi M., Yamamoto M., Nakamura K. (1993) The effect of superoxide production on the replantation of rat limbs after cold ischemia. J Reconstr Microsurg 9:61–68

    Article  PubMed  CAS  Google Scholar 

  30. Yokoyama K., Homan M., Takagishi K., Sekiguchi M., Yamamoto M. (1992) Protective effects of coenzyme Q10 on ischemia-induced reperfusion injury in ischemic limb models. Plast Reconstr Surg 90:890–898

    Article  PubMed  CAS  Google Scholar 

  31. Whitney T.M., Wang K.K., Sternbach Y., Chaklis-Haley D. (1997) Reduction of ischemic reperfusion edema with corticotropin-releasing factor (CRF) in rat hind limb replantation. Ann Plast Surg 38:416–419

    Article  PubMed  CAS  Google Scholar 

  32. Kihira M., Miura T., Ishiguro N. (1991) Preservation of skeletal muscle in tissue transfers using rat hind limbs. Plast Reconstr Surg 88:275–284

    Article  PubMed  CAS  Google Scholar 

  33. Norden M.A., Rao V.K., Southard J.H. (1997) Improved preservation of rat hind limbs with the University of Wisconsin solution and butanedione monoxine. Plast Reconstr Surg 100:957-965

    Google Scholar 

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© 2003 Springer Japan

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Minami, A., Iwasaki, N. (2003). Limb Replantation in the Rat. In: Tamai, S., Usui, M., Yoshizu, T. (eds) Experimental and Clinical Reconstructive Microsurgery. Springer, Tokyo. https://doi.org/10.1007/978-4-431-67865-6_6

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  • DOI: https://doi.org/10.1007/978-4-431-67865-6_6

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-67998-1

  • Online ISBN: 978-4-431-67865-6

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