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Pathological Findings of Ossification of the Posterior Longitudinal Ligament and Ossification of the Spinal Ligaments in an Experimental Animal Model

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OPLL

Abstract

Patients with ossification of the posterior longitudinal ligament (OPLL) exhibit severe paralysis of the spinal cord, and such cases are classified as a recalcitrant disease by the Japanese Ministry of Health and Welfare. However, the etiology of this condition has not yet been clarified. The first report in Japan was made by Tsukimoto [1] in 1960, and in 1975 the Japanese Ministry of Health and Welfare research group was formed. Initially, investigations centered on cases of OPLL, but when it was discovered that ossification develops in various spinal ligaments, the concept of ossification of the spinal ligaments (OSL) became established.

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References

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Authors and Affiliations

  1. Department of Orthopedic Surgery, Tokyo Medical College, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160, Japan

    Yukio Miura, Ryo Hikone, Kengo Yamamoto, Kiyoshi Kawai, Satoshi Tanaka & Atsuhiro Imakiire

Authors
  1. Yukio Miura
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  2. Ryo Hikone
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  3. Kengo Yamamoto
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  4. Kiyoshi Kawai
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  5. Satoshi Tanaka
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  6. Atsuhiro Imakiire
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Editor information

Editors and Affiliations

  1. Department of Orthopaedic Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka, 565, Japan

    Kazuo Yonenobu M.D., D. Med. Sc. (Associate Professor) (Associate Professor)

  2. Department of Orthopaedic Surgery, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890, Japan

    Takashi Sakou M.D. (Professor and Chairman) (Professor and Chairman)

  3. Osaka University, 4-2-78 Fukushima, Fukushima-ku, Osaka, 553, Japan

    Keiro Ono M.D., Ph.D. (Professor Emeritus. Director) (Professor Emeritus. Director)

  4. Osaka Koseinenkin Hospital, 4-2-78 Fukushima, Fukushima-ku, Osaka, 553, Japan

    Keiro Ono M.D., Ph.D. (Professor Emeritus. Director) (Professor Emeritus. Director)

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© 1997 Springer Japan

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Miura, Y., Hikone, R., Yamamoto, K., Kawai, K., Tanaka, S., Imakiire, A. (1997). Pathological Findings of Ossification of the Posterior Longitudinal Ligament and Ossification of the Spinal Ligaments in an Experimental Animal Model. In: Yonenobu, K., Sakou, T., Ono, K. (eds) OPLL. Springer, Tokyo. https://doi.org/10.1007/978-4-431-67046-9_5

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  • DOI: https://doi.org/10.1007/978-4-431-67046-9_5

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-67048-3

  • Online ISBN: 978-4-431-67046-9

  • eBook Packages: Springer Book Archive

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