Other Products Being Developed by Pharmaceutical and Cosmetic Companies

  • Masumi Inaba
  • Yoshikata Inaba


Minoxidil is a piperidenopyrimidine derivative and a potent peripheral arteriolar vasodilator used in the treatment of resistant hypertension (Ducharme et al. 1973; Mehta et al. 1975; Novak et al. 1985). It is marketed by the Upjohn Pharmaceutical Company (MI, USA) under the trade name Loniten. The drug has several side effects. On the negative side, it may cause edema, reduced blood pressure, tachycardia, nausea, dyspnea, and anemia (Mehta et al. 1975; Devine et al. 1977). The positive side effect of Loniten, however, is regeneration of hair growth in the temporal area (Burton and Marshall 1979b; Seidman et al. 1981; Fiedler-Weiss 1987). Hypertrichosis is a frequent (30%–100% in different reports) side effect of oral therapy in adults (Burton and Marshall 1979b; Seidman et al. 1981).


Hair Follicle Hair Growth Resistant Hypertension Bullous Pemphigoid Alopecia Areata 
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Copyright information

© Springer Japan 1996

Authors and Affiliations

  • Masumi Inaba
    • 1
  • Yoshikata Inaba
    • 2
    • 3
  1. 1.Department of Aesthetic Plastic SurgeryInaba ClinicSuginami-ku, Tokyo, 166Japan
  2. 2.Department of DermatologyThe Jikei University School of MedicineMinato-ku, Tokyo, 105Japan
  3. 3.Department of DermatologyInaba Aesthetic Plastic SurgerySuginami-ku, Tokyo, 166Japan

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