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Summary

After general anesthesia, shivering is a common complication in both normothermic and hypothermic patients. Electromyographically, but not clinically, it is possible to distinguish between thermoregulatory shivering and nonthermoregulatory shivering. The second might be caused by postoperative pain or residual concentrations of volatile anesthetics producing spinal hyperreflexia. Postanesthetic shivering mainly contributes to patient discomfort and, moreover, also to morbidity by increasing oxygen demand and elevating intraocular or possibly intracranial pressure. Prevention or therapy of postanesthetic shivering includes the maintenance of normothermia, adequate pain therapy, and the administration of opioids, especially meperidine, α2-agonists, or the 5-HT3 antagonist dolasetron.

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References

  1. Matsukawa T, Sessler DI, Sessler AM, et al (1995) Heat flow and distribution during induction of general anesthesia. Anesthesiology 82: 662–673

    Article  PubMed  CAS  Google Scholar 

  2. Sessler DI (1997) Mild perioperative hypothermia. N Engl J Med 336: 1730–1737

    Article  PubMed  CAS  Google Scholar 

  3. Bock M, Müller J, Bach A, et al (1998) Effects of preinduction and intraoperative warming during major laparotomy. Br J Anaesth 80: 159–163

    Article  PubMed  CAS  Google Scholar 

  4. Frank SM, Higgins MS, Breslow MJ, et al (1995) The catecholamine, cortisol, and hemodynamic responses to mild perioperative hypothermia. Anesthesiology 82: 8393

    Article  Google Scholar 

  5. Vaughan MS, Vaughan RW, Cork RC (1981) Postoperative hypothermia in adults: relationship of age, anesthesia, and shivering to rewarming. Anesth Ana1g 60: 746751

    Google Scholar 

  6. IUPS Thermal Commission (1987) Glossary of terms for thermal physiology. Pflügers Arch 410: 567–587

    Article  Google Scholar 

  7. Horn EP, Sessler DI, Standl T, et al (1998) Nonthermoregulatory shivering in patients recovering from isoflurane or deflurane anesthesia. Anesthesiology 89: 878–886

    Article  PubMed  CAS  Google Scholar 

  8. Horn EP, Schroeder F, Wilhelm S, et al (1999) Postoperative pain facilitates nonthermoregulatory tremor. Anesthesiology 91: 979–984

    Article  PubMed  CAS  Google Scholar 

  9. Shimoji K, Fujiwara N, Fukuda S, et al (1990) Effects of isoflurane on spinal inhibitory potentials. Anesthesiology 72: 851–857

    Article  PubMed  CAS  Google Scholar 

  10. Leslie K, Sessler DI (1996) Reduction in the shivering threshold is proportional to spinal block height. Anesthesiology 84: 1327–1331

    Article  PubMed  CAS  Google Scholar 

  11. Kim JS, Ikeda T, Sessler DI, et al (1998) Epidural anesthesia reduces the gain and maximum intensity of shivering. Anesthesiology 88: 851–857

    Article  PubMed  CAS  Google Scholar 

  12. Philip J, Alexander JM, Sharma SK, et al (1999) Epidural analgesia during labor and maternal fever. Anesthesiology 90: 1271–1275

    Article  PubMed  CAS  Google Scholar 

  13. Panzer O, Ghazanfari N, Sessler DI, et al (1999) Shivering and shivering-like tremor during labor with and without epidural analgesia. Anesthesiology 90: 1609–1616

    Article  PubMed  CAS  Google Scholar 

  14. Crossley AWA (1992) Six months of shivering in a district general hospital. Anaesthesia 47: 845–847

    Article  PubMed  CAS  Google Scholar 

  15. Kurz A, Plattner O, Sessler DI, et al (1993) The threshold for thermoregulatory vasoconstriction during nitrous oxide/isoflurane anesthesia is lower in elderly than in young patients. Anesthesiology 79: 465–469

    Article  PubMed  CAS  Google Scholar 

  16. Vassilieff N, Rosencher N, Sessler DI, et al (1995) Shivering threshold during spinal anesthesia is reduced in elderly patients. Anesthesiology 83: 1162–1166

    Article  PubMed  CAS  Google Scholar 

  17. Lyons B, Taylor A, Power C, et al (1996) Postanaesthetic shivering in children. Anaesthesia 51: 442–445

    Article  PubMed  CAS  Google Scholar 

  18. Sessler DI, Rubinstein EH, Moayeri A (1991) Physiologic responses to perianesthetic hypothermia in humans. Anesthesiology 75: 594–610

    Article  PubMed  CAS  Google Scholar 

  19. Frank SM, Fleisher LA, Olson KF (1995) Multivariate determinants of early postoperative oxygen consumption in elderly patients. Anesthesiology 83: 241–249

    Article  PubMed  CAS  Google Scholar 

  20. Frank SM, Fleisher LA, Breslow MJ (1997) Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events. JAMA 277: 1127–1134

    Article  PubMed  CAS  Google Scholar 

  21. Mahajan R, Grover VK, Sharma SL, et al (1987) Intraocular pressure changes during muscular hyperactivity after general anesthesia. Anesthesiology 66: 419–421

    Article  PubMed  CAS  Google Scholar 

  22. Hamilton WF, Woodburg RA, Harper HAT (1944) Arterial, cerebrospinal and venous pressure in man during cough and strain. Am J Physiol 141: 42–50

    Google Scholar 

  23. Sharkey A, Lipton JM, Murphy MT, et al (1987) Inhibition of postanesthetic shivering with radiant heat. Anesthesiology 66: 249–252

    Article  PubMed  CAS  Google Scholar 

  24. Just B, Delva E, Camus Y, et al (1992) Oxygen uptake during recovery following naloxone. Anesthesiology 76: 60–64

    Article  PubMed  CAS  Google Scholar 

  25. Wrench IJ, Cavill G, Ward JEH, et al (1997) Comparison between alfentanil, pethidine and placebo in the treatment of post-anaesthetic shivering. Br J Anaesth 79: 541–542

    Article  PubMed  CAS  Google Scholar 

  26. Macintyre PE, Pavlin EG, Dwersteg JF (1987) Effect of meperidine on oxygen consumption, carbon dioxide production, and respiratory gas exchange in postanesthesia shivering. Anesth Analg 66: 751–755

    Article  PubMed  CAS  Google Scholar 

  27. Kurz A, Ikeda T, Sessler DI, et al (1997) Meperidine decreases the shivering threshold twice as much as the vasoconstriction threshold. Anesthesiology 86: 1046–1054

    Article  PubMed  CAS  Google Scholar 

  28. Kurz M, Belani KG, Sessler DI, et al (1993) Naloxone, meperidine, and shivering. Anesthesiology 79: 1193–1201

    Article  PubMed  CAS  Google Scholar 

  29. Wang JJ, Ho ST, Lee SC, et al (1999) A comparison among nalbuphine, meperidine, and placebo for treating postanesthetic shivering. Anesth Analg 88: 686–689

    PubMed  CAS  Google Scholar 

  30. DeWitte J, Deloof T, DeVeylder J, et al (1997) Tramadol in the treatment of postanesthetic shivering. Acta Anaesthesiol Scand 41: 506–510

    Article  CAS  Google Scholar 

  31. Ikeda T, Sessler DI, Tayefeh F, et al (1998) Meperidine and alfentanil do not reduce gain or maximum intensity of shivering. Anesthesiology 88: 858–865

    Article  PubMed  CAS  Google Scholar 

  32. Cui Y, Lee TF, Wang LCH (1997) Possible involvement of the serotonergic system in intraseptal opioid-induced hypothermia in ground squirrels. Proc N Y Acad Sci 813: 192–196

    Article  CAS  Google Scholar 

  33. Delauny L, Bonnet F, Duvaldestin P (1991) Clonidine decreases postoperative oxygen consumption in patients recovering from general anaesthesia. Br J Anaesth 67: 397–401

    Article  Google Scholar 

  34. Joris J, Banache M, Bonnet F, et al (1993) Clonidine and ketanserin both are effective treatment for postanesthetic shivering. Anesthesiology 79: 532–539

    Article  PubMed  CAS  Google Scholar 

  35. Delaunay L, Bonnet F, Liu N, et al (1993) Clonidine comparably decreases the thermoregulatory thresholds for vasoconstriction and shivering in humans. Anesthesiology 79: 470–474

    Article  PubMed  CAS  Google Scholar 

  36. Talke P, Tayefeh F, Sessler DI, et al (1997) Dexmedetomidine does not alter the sweating threshold, but comparably and linearly decreases the vasoconstriction and shivering threshold. Anesthesiology 87: 835–841

    Article  PubMed  CAS  Google Scholar 

  37. Ittner KP, Bucher M, Riebel K, et al (1996) Uradipil, an a,-adrenergic-antagonist/5HT1A-agonist, suppresses cold induced shivering in man (abstract). Anesthesiology 85: A170

    Google Scholar 

  38. Horn EP, Standl T, Sessler DI, et al (1998) Physostigmine prevents postanesthetic shivering as does meperidine or clonidine. Anesthesiology 88: 108–113

    Article  PubMed  CAS  Google Scholar 

  39. Kizilirmak S, Karakas SE, Akca O, et al (1997) Magnesium sulfate stops postanesthetic shivering. Proc N Y Acad Sci 813: 799–806

    Article  CAS  Google Scholar 

  40. Wrench IJ, Singh P, Dennis AR, et al (1997) The minimum effective doses of pethidine and doxapram in the treatment of post-anaesthetic shivering. Anaesthesia 52: 32–36

    Article  PubMed  CAS  Google Scholar 

  41. Rosa G, Pinto G, De Blasi RA, et al (1995) Control of post anesthetic shivering with nefopam hydrochloride in mildly hypothermic patients after neurosurgery. Acta Anaesthesiol Scand 39: 90–95

    Article  PubMed  CAS  Google Scholar 

  42. Rosa G, Dell’Utri D, Conti G, et al (1997) Efficacy of nefopam for the prevention and treatment of amphotericin B-induced shivering. Arch Intern Med 157: 1589–1592

    Article  PubMed  CAS  Google Scholar 

  43. Zeisberger E, Roth J (1996) Central regulation of adaptive responses to heat and cold. In: Fregly MJ, Blatteis CM (eds) Environmental physiology, vol 1. Handbook of physiology, section 4. American Physiological Society, Oxford University Press, Oxford, pp 579–595

    Google Scholar 

  44. Bruck K, Zeisberger E (1990) Adaptive changes in thermoregulation and their neuropharmacological basis. In: Schönbaum E, Lomax P (eds) Thermoregulation: physiology and biochemistry. Pergamon, New York, pp 255–307

    Google Scholar 

  45. Bock M, Sinner B, Göttlicher M, et al (1999) Dolasetron prevents postanesthetic shivering (abstract). Anesthesiology 91: A1184

    Google Scholar 

  46. Miller RC, Galvan M, Gittos MW, et al (1993) Pharma cological properties of dolasetron, a potent and selective antagonist at 5-HT3 receptors. Drug Dev Res 28: 87–93

    Article  CAS  Google Scholar 

  47. Frank SM, Raja SN, Wu PK, et al (1997) a-Adrenergic mechanism of thermoregulation in humans. Proc N Y Acad Sci 813: 101–110

    Google Scholar 

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© 2001 Springer Japan

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Bock, M., Motsch, J. (2001). Postanesthetic Shivering. In: Kosaka, M., Sugahara, T., Schmidt, K.L., Simon, E. (eds) Thermotherapy for Neoplasia, Inflammation, and Pain. Springer, Tokyo. https://doi.org/10.1007/978-4-431-67035-3_17

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  • DOI: https://doi.org/10.1007/978-4-431-67035-3_17

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-67037-7

  • Online ISBN: 978-4-431-67035-3

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