Itai-Itai Disease and Countermeasures Against Cadmium Pollution by the Kamioka Mine

  • Fumikazu Yoshida


Osteomalacia, softening of the bones as a result of renal tubular dysfunction, is now commonly known as Itai-Itai disease. Osteomalacia occurs in women who have borne several children. During the final stages of osteomalacia, when patients can neither stand, walk, nor talk, all they say is itai-itai (Japanese for “It hurts! It hurts!”), hence its common name. In one of the worst cases of the disease, a patient lost 30 cm in height as a result of pressure fractures of the vertebrae; and another patient suffered many fractures, 28 in the ribs alone.


Cadmium Level Renal Tubular Dysfunction Cadmium Pollution Electrolysis Plant Zinc Electrolysis Plant 
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Copyright information

© Springer Japan 2002

Authors and Affiliations

  • Fumikazu Yoshida
    • 1
  1. 1.Graduate School of EconomicsHokkaido UniversitySapporoJapan

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