History and Concept of Dendritic Cells
In 1868, medical student Paul Langerhans discovered a population of dendritically shaped cells in the suprabasal region of the epidermis. These cells now bear his name. The reactivity of these cells to gold salt made him believe that they represented sensory nerve endings. However, today we know that Langerhans cells (LCs) are dendritic leukocytes, which perform a variety of activities; in particular, they function as professional antigen-presenting cells (APCs).
KeywordsDendritic Cell Sensory Nerve Ending Dendritic Cell Precursor Defective Functioning Dendritic Cell Producer
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