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Applications for Purification and Screening

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Real-Time Analysis of Biomolecular Interactions

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Abstract

Receptor protein-tyrosine kinases (RTKs) , as receptors for many growth and differentiation factors, have critical functions for many biological processes. Whereas RTKs can be categorized into many families, every RTK has a kinase domain, whose amino acid sequence is conserved among RTKs, in an intercellular portion. However, in the extracellular portion, RTKs have ligand-binding domains which are quite different between families.

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Author information

Authors and Affiliations

  1. Central Technology Laboratory, Asahi Chemical Industry Co. Ltd., 2-1 Samejima, Fuji, 416-8501, Japan

    Seiji Sakano

  2. Kumamoto University School of Medicine, 2-2-2 Honjo, Kumamoto, 860-0811, Japan

    Toshio Suda

  3. Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan

    Kazuo Shin-ya & Haruo Seto

  4. Department of Immunotechnology, Lund University, P.O. Box 7031, S-220 07, Lund, Sweden

    Ann-Christin Malmborg

Authors
  1. Seiji Sakano
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  2. Toshio Suda
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  3. Kazuo Shin-ya
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  4. Haruo Seto
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  5. Ann-Christin Malmborg
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Editor information

Editors and Affiliations

  1. Institute for Frontier Medical Sciences, Kyoto University, 53 Kawahara-cho Shogoin, 606-8507, Sakyo-ku, Kyoto, Japan

    Kazuhiro Nagata

  2. Frontier Collaborative Research Center, Tokyo Institute of Technology, 4259 Nagatsuta-cho, 226-8503, Midori-ku, Yokonhama, Japan

    Hiroshi Handa

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© 2000 Springer Japan

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Sakano, S., Suda, T., Shin-ya, K., Seto, H., Malmborg, AC. (2000). Applications for Purification and Screening. In: Nagata, K., Handa, H. (eds) Real-Time Analysis of Biomolecular Interactions. Springer, Tokyo. https://doi.org/10.1007/978-4-431-66970-8_18

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  • DOI: https://doi.org/10.1007/978-4-431-66970-8_18

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-66972-2

  • Online ISBN: 978-4-431-66970-8

  • eBook Packages: Springer Book Archive

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