Applications for Purification and Screening

  • Seiji Sakano
  • Toshio Suda
  • Kazuo Shin-ya
  • Haruo Seto
  • Ann-Christin Malmborg


Receptor protein-tyrosine kinases (RTKs) , as receptors for many growth and differentiation factors, have critical functions for many biological processes. Whereas RTKs can be categorized into many families, every RTK has a kinase domain, whose amino acid sequence is conserved among RTKs, in an intercellular portion. However, in the extracellular portion, RTKs have ligand-binding domains which are quite different between families.


Phage Display Antibody Fragment Sensor Chip Response Unit Ligand Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Japan 2000

Authors and Affiliations

  • Seiji Sakano
    • 1
  • Toshio Suda
    • 2
  • Kazuo Shin-ya
    • 3
  • Haruo Seto
    • 3
  • Ann-Christin Malmborg
    • 4
  1. 1.Central Technology LaboratoryAsahi Chemical Industry Co. Ltd.FujiJapan
  2. 2.Kumamoto University School of MedicineKumamotoJapan
  3. 3.Institute of Molecular and Cellular BiosciencesThe University of TokyoBunkyo-ku, TokyoJapan
  4. 4.Department of ImmunotechnologyLund UniversityLundSweden

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