Recently, the requirement for gene diagnosis has increased as the number of causal genes that have been found has increased. There are ethical problems, yet gene therapy has been popular. Medical treatments have been intimately connected with genetics. Here BIACORE applications in the medical field are also described beside mismatch detection.
KeywordsSensor Chip Affinity Constant Complementary Region Gene Diagnosis Single Mismatch
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- 2.Gotoh M, Hasebe M, Ohira T, Tosu M (1997) Gene diagnosis with an affinity sensor. BIACORE: principles and applications(in Japanese). Rinsho-Byori 4:224–228Google Scholar
- 3.Gotoh M (1997) Affinity sensor (BIACORE) based on surface plasmon resonance (in Japanese). Kensa-To-Gijutsu 25:785–787Google Scholar
- 5.Gotoh M (1997) DNA analysis with a biosensor based on surface plasmon resonance (in Japanese). Igaku-No-Ayumi 183:429–432Google Scholar