Recent studies have revealed that various protein factors have important roles in gene expression. These factors are involved in transcriptional regulation not only by binding to the promoter region of DNA with sequence specificity but also by interacting with one another on DNA. It has also been revealed that some factors bind to DNA indirectly to regulate transcription. These factors, which are called cofactors, are recruited on promoter regions by protein-protein interactions. The mechanism of transcriptional regulation includes many of interactions among biomolecules.
KeywordsSurface Plasmon Resonance Sensor Surface Sensor Chip Dissociation Rate Constant Cyclobutane Pyrimidine Dimer
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