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Two Major Pumps of the Heart: Difference and Interdependence of the Right and Left Ventricles

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New Horizons for Failing Heart Syndrome

Abstract

The right and left ventricles are the two major pumps of the heart that deliver blood to the pulmonary and systemic circulations, respectively. Both ventricles propel the same amount of blood but are different with regard to intracavitary pressure, wall thickness, and shape. Coronary perfusion pressure and regional wall motion are closely linked to myocardial metabolic states and regional myocardial blood flow. When coronary perfusion pressure is decreased below the level of coronary flow autoregulation, regional wall motion deteriorates. However, the mechanism of a reduced level of autoregulation in the right coronary artery remains unclear. The transmural distribution of myocardial necrosis was also different between right and left coronary artery ligations. The interdependence of the right and left ventricles is clearly seen. The resetting of regional diastolic lengths may affect systolic and diastolic functions. Thus the structural and hemodynamic differences of these two pumping chambers determine the perfusion pressure-flow function integrity of the regional myocardium and the distribution of myocardial necrosis. Understanding the interdependence of these chambers will allow us to develop a better assist mechanism for depressed pump performance.

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Author information

Author notes

  1. Yoshitoshi Urabe

    Present address: Kitakyushu Medical Center, Kitakyushu 802, Japan

  2. Keizaburo Ohzono

    Present address: Kyushu Medical Center, Fukuoka 812, Japan

Authors and Affiliations

  1. First Department of Internal Medicine, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata, 990-23, Japan

    Hitonobu Tomoike, Yoshitoshi Urabe, Keizaburo Ohzono & Seiji Yamaguchi

Authors
  1. Hitonobu Tomoike
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  2. Yoshitoshi Urabe
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  3. Keizaburo Ohzono
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  4. Seiji Yamaguchi
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Editor information

Editors and Affiliations

  1. Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan

    Shigetake Sasayama M.D.

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© 1996 Springer Japan

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Tomoike, H., Urabe, Y., Ohzono, K., Yamaguchi, S. (1996). Two Major Pumps of the Heart: Difference and Interdependence of the Right and Left Ventricles. In: Sasayama, S. (eds) New Horizons for Failing Heart Syndrome. Springer, Tokyo. https://doi.org/10.1007/978-4-431-66945-6_5

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  • DOI: https://doi.org/10.1007/978-4-431-66945-6_5

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-66947-0

  • Online ISBN: 978-4-431-66945-6

  • eBook Packages: Springer Book Archive

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