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Plasma Levels of Thrombomodulin and Active Plasminogen Activator Inhibitor Increase in Disseminated Intravascular Coagulation with Multiple Organ Failure

  • H. Asakura
  • H. Jokaji
  • M. Saito
  • C. Uotani
  • I. Kumabashiri
  • E. Morishita
  • M. Yamazaki
  • T. Matsuda
Conference paper

Abstract

Disseminated intravascular coagulation (DIC) is a serious clinical condition, but its pathophysiology is very different according to the underlying diseases responsible for DIG, For example, a marked activation of the coagulation and fibrinolytic system is present in most cases of acute promyelocytic leukemia. On the contrary, a little activation of the fibrinolytic system is present in most cases of sepsis with DIC1–4. Therefore, it is important to investigate these pathologic condithions separately according to the underlying disease responsible for DIC.

Keywords

Disseminate Intravascular Coagulation Acute Promyelocytic Leukemia Multiple Organ Failure Disseminate Intravascular Coagulation Blastic Crisis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Japan 1992

Authors and Affiliations

  • H. Asakura
    • 1
  • H. Jokaji
    • 1
  • M. Saito
    • 1
  • C. Uotani
    • 1
  • I. Kumabashiri
    • 1
  • E. Morishita
    • 1
  • M. Yamazaki
    • 1
  • T. Matsuda
    • 1
  1. 1.Department of Internal Medicine (III)Kanazawa University School of MedicineKanazawaJapan

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