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Haemostatic Studies in Uraemic Patients Following DDAVP Administration

  • M. Mysliwiec
  • J. S. Malyszko
  • J. Malyszko
  • M. Pietraszek
  • A. Azzadin
  • W. Buczko
Conference paper

Abstract

Chronic renal failure is associated with various haemostatic defects.Patients with chronic renal failure have increased bleeding tendency. The laboratory parameter which appears to correlate the best with the risk of haemorrhage is the bleeding time. Current therapy to correct uraemic bleeding includes dialysis intensification,blood and cryoprecipitate transfusions, estrogens or 1-deamino-8 -D -arginine vasopressin (DDAVP, desmopressin). DDAVP is a synthetic vasopressin analogue devoid of vasoconstrictory action which shortens the bleeding time in patients with mild haemophilia [l],von Willebrand disease [1] or platelet function defects [2,3].

Keywords

Plasminogen Activator Inhibitor Bleeding Time Uraemic Patient Plasminogen Activator Inhibitor Activity Mild Haemophilia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Japan 1992

Authors and Affiliations

  • M. Mysliwiec
    • 1
  • J. S. Malyszko
    • 1
  • J. Malyszko
    • 1
  • M. Pietraszek
    • 2
  • A. Azzadin
    • 2
  • W. Buczko
    • 2
  1. 1.Nephrology DepartmentsMedical SchoolBialystokPoland
  2. 2.Pharmacodynamics DepartmentsMedical SchoolBialystokPoland

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