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Haemostatic Studies in Uraemic Patients Following DDAVP Administration

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Hemostasis and Circulation

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Abstract

Chronic renal failure is associated with various haemostatic defects.Patients with chronic renal failure have increased bleeding tendency. The laboratory parameter which appears to correlate the best with the risk of haemorrhage is the bleeding time. Current therapy to correct uraemic bleeding includes dialysis intensification,blood and cryoprecipitate transfusions, estrogens or 1-deamino-8 -D -arginine vasopressin (DDAVP, desmopressin). DDAVP is a synthetic vasopressin analogue devoid of vasoconstrictory action which shortens the bleeding time in patients with mild haemophilia [l],von Willebrand disease [1] or platelet function defects [2,3].

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References

  1. Mannucci PM. Ruggeri ZM. Pareti FJ. Capitanio A (1977) Lancet 1: 869–872

    Article  PubMed  CAS  Google Scholar 

  2. Kobrinsky NL. Israels ED. Gerrard JM. Cheang MS. Watson CM. Bishop AJ. Schroeder ML (1984) Lancet 1: 1145–1148

    Article  PubMed  CAS  Google Scholar 

  3. Schulman S. Johnsson H. Edberg N. Blomback N (1987) Thromb Res 45: 165–174

    Article  PubMed  CAS  Google Scholar 

  4. Watson AJS. Koegh JAB (1982) Nephron 4:260–261

    Google Scholar 

  5. Mannucci PM. Remuzzi G. Pusineri F. Lombardi R. Valsecchi C. Mecca G. Zimmerman TS (1983) N Engl J Med 308: 8–12

    Article  PubMed  CAS  Google Scholar 

  6. Rydzewski A. Rowinski M. Mysliwiec M (1986) Folia Haematol (Leipzig) 113: 823–830

    CAS  Google Scholar 

  7. Malyszko J. Pietraszek M. Buczko W. Mysliwiec M (1990) Folia Haematol (Leipzig) 117: 319–324

    CAS  Google Scholar 

  8. Ruggeri ZM. Mannucci PM. Lombardi R. Federici AB. Zimmerman TS (1981) Blood 59: 1272–12

    Google Scholar 

  9. Grant MB. Guay C. Lottenberg R (1988) Thromb Haemostas 59: 269–272

    CAS  Google Scholar 

  10. DeClerk T. Somers Y. van Gorp L (1984) Agents Action 15: 627–635

    Article  Google Scholar 

  11. Mielke CH. Kaneshiro JA. Maher JA. Wessler JM. Rapaport SI (1969) Blood 34: 204–215

    PubMed  Google Scholar 

  12. Laurell CB (1966) Anal Biochem 15: 45–52

    Article  PubMed  CAS  Google Scholar 

  13. Bukh A. Ingerslev J. Stenbjerg S. Hundahl-Moller NP (1986) Thromb Res 43: 579–585

    Article  PubMed  CAS  Google Scholar 

  14. Achroft G. Crawford TB (1964) Clin Chim Acta 9: 364–369

    Article  Google Scholar 

  15. Drummond AH. Gordon JL (1974) Thromb Diathes haemorrh (Stuttgart) 31: 366

    CAS  Google Scholar 

  16. Lingjaerde D (1979) Acta Pharmacol Toxicol 45: 394

    Article  CAS  Google Scholar 

  17. Gordon JL. Olverman HJ (1978) Brit J Pharmacol 62: 219

    Article  CAS  Google Scholar 

  18. Kowarzyk H. Buluk K (1950) Post Hig Med Dosw 2: 1–76

    CAS  Google Scholar 

  19. Chmielewska JN. Wiman B (1985) Clin Chem 32: 482–485

    Google Scholar 

  20. DiMichele DM. Hatheway WME (1990) Am J Haematol 33: 39–45

    Google Scholar 

  21. Moffat EH. Giddings JC. Bloom AL (1984) Brit J Haematol 57: 651–652

    CAS  Google Scholar 

  22. Mannucci PM. Canciani MZ. Roto L. Donovani BS (1979) Brit J Haematol 43: 283–293

    Google Scholar 

  23. Brommer EJP. Derkx FHM. Barret-Bergshoeff MM. Schalekamp MADH (1984) Thromb Haemostas 51: 42–44

    CAS  Google Scholar 

  24. D’Angelo A. Capitanio A. Smith JB. Vasecchi C. Mannucci PM (1983) Thromb Haemostas 49: 64

    Google Scholar 

  25. Malyszko J. Pietraszek M. Azzadin A. Buczko W. Mysliwiec M (1990) Thromb Haemostas 61: 637

    Google Scholar 

  26. Yang X. Disa J. Rao AK (1990) Thromb Res 59: 809–810

    Article  PubMed  CAS  Google Scholar 

  27. Soslau G. Schwartz AB. Putatunda B. Conroy JD. Parker J. Abel RF. Brodsky I (1990) Am J Med Sciences 299; 372–379

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Nephrology Departments, Medical School, Bialystok, Poland

    M. Mysliwiec, J. S. Malyszko & J. Malyszko

  2. Pharmacodynamics Departments, Medical School, Bialystok, Poland

    M. Pietraszek, A. Azzadin & W. Buczko

Authors
  1. M. Mysliwiec
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  2. J. S. Malyszko
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  3. J. Malyszko
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  4. M. Pietraszek
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  5. A. Azzadin
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  6. W. Buczko
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Editor information

Editors and Affiliations

  1. Department of Physiology, Hamamatsu University, School of Medicine, 431-31, Hamamatsu, Shizuoka, Japan

    A. Takada

  2. Department of Biochemistry, Temple University, School of Medicine, Philadelphia, USA

    A. Z. Budzynski

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© 1992 Springer Japan

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Mysliwiec, M., Malyszko, J.S., Malyszko, J., Pietraszek, M., Azzadin, A., Buczko, W. (1992). Haemostatic Studies in Uraemic Patients Following DDAVP Administration. In: Takada, A., Budzynski, A.Z. (eds) Hemostasis and Circulation. Springer, Tokyo. https://doi.org/10.1007/978-4-431-66925-8_27

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  • DOI: https://doi.org/10.1007/978-4-431-66925-8_27

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-70096-8

  • Online ISBN: 978-4-431-66925-8

  • eBook Packages: Springer Book Archive

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