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The Effect of Human Granulocytic Neutral Proteases on Hemostasis: Effects of Cathepsin G on Platelets

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Hemostasis and Circulation

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Abstract

Human nsmtrophil elastase (HNE) and cathepsin G (Cat G) are serine proteases active at neutral pH (1, 2, 3) and both are released from polymorphonuclear (PMN) azurophilic granules during phagocytosis, blood coagulation, strenuous exercise, under the influence of immune complexes, chemotacti c peptides and sodium urate crystals (4).

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Author information

Authors and Affiliations

  1. Laboratory of Blood Coagulation and Hemostasis, Institute of Hematology, Warsaw, Poland

    Maria Kopec & Ksenia Bykowska

Authors
  1. Maria Kopec
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  2. Ksenia Bykowska
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Editor information

Editors and Affiliations

  1. Department of Physiology, Hamamatsu University, School of Medicine, 431-31, Hamamatsu, Shizuoka, Japan

    A. Takada

  2. Department of Biochemistry, Temple University, School of Medicine, Philadelphia, USA

    A. Z. Budzynski

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© 1992 Springer Japan

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Kopec, M., Bykowska, K. (1992). The Effect of Human Granulocytic Neutral Proteases on Hemostasis: Effects of Cathepsin G on Platelets. In: Takada, A., Budzynski, A.Z. (eds) Hemostasis and Circulation. Springer, Tokyo. https://doi.org/10.1007/978-4-431-66925-8_10

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  • DOI: https://doi.org/10.1007/978-4-431-66925-8_10

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-70096-8

  • Online ISBN: 978-4-431-66925-8

  • eBook Packages: Springer Book Archive

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