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The Influence of Cold on the Recovery Index of Vecuronium and Decamethonium in Man

  • A. J. England
  • K. Richards
  • I. Redai
  • X. Wu
  • S. Feldman
Conference paper

Abstract

We have used the change in rate of reaction with temperature to establish the mode of recovery of vecuronium, vec, and decamethonium, dec, in man. The increase in rate of reaction for a 10°C rise in temperature (Q10) for a physical reaction, such as diffusion, is about 1.5 and a biological reaction, such as conformation change in receptor structure on ligand binding, about 2.8 [1].

Keywords

Biological Reaction Conformation Change Receptor Structure Adductor Policis Physical Reaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. [1]
    Hill AV. Journal of Physiology of London 1909 39;361–373.Google Scholar
  2. [2]
    Feldman SA, Tyrell MF. Proceedings of the Royal Society of Medicine 1970 63;692–695.PubMedGoogle Scholar
  3. [3]
    Glavinovic MI, Law Min JC, Kapural L, Donati F, Bevan DR. Journal of Pharmacology and Experimental Theraputics 1993 265;1181–1186.Google Scholar

Copyright information

© Springer Japan 1995

Authors and Affiliations

  • A. J. England
    • 1
  • K. Richards
    • 1
  • I. Redai
    • 1
  • X. Wu
    • 1
  • S. Feldman
    • 1
  1. 1.Magill Department of AnaesthesiaChelsea and Westminster HospitalLondonUK

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