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Comparative Studies of Pipecuronium and Tubocurarine on Releases of Histamine and N-Methylhistamine in Surgical Patients

  • E. Ueda
  • J. Takeda
  • J. Takahashi
  • K. Fukushima
Conference paper

Abstract

It has been reported that there is no evidence of plasma histamine (HA) release by the intravenous administration of pipecuronium (PPB) in humans(1). It is well recognized that the half life of released plasma histamine (HA) is very short but that of n-methylhistamine (n-MHA) , a metabolite, is much longer. Assaying both HA and n-MHA would reveal the extent to which HA appears in plasma. This study was undertaken to assess pipecuronium (PPB) induced release of HA compared with tubocurarine (d-Tc) by measuring both HA and n-MHA in plasma.

Keywords

Public Health Blood Pressure Heart Rate Blood Sample Informed Consent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1).
    Brit.J.Anaesth 1991:67:320Google Scholar

Copyright information

© Springer Japan 1995

Authors and Affiliations

  • E. Ueda
    • 1
  • J. Takeda
    • 1
  • J. Takahashi
    • 1
  • K. Fukushima
    • 1
  1. 1.Department of AnesthesiologyKeio University, School of MedicineShinjuku-ku, Tokyo, 160Japan

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