Recovery and Reversal of Mivacurium Neuromuscular Blockade with Neostigmine and Edrophonium in Paediatric Patients
Mivacurium (MIV), a new short-acting nondepolarizing muscle relaxant, is metabolized by plasmacholinesterase. In children intubating doses of 0.2 mg. kg 1 take 8.4 min to recover 5% and 95% T1 is reached 9.7 min later 1. If neostigmine (NEOS) or edrophonium (EDRO) accelerates MIV recovery, then it may approach the duration of action of succinylcholine.
KeywordsSpontaneous Recovery Final Height Recovery Data Adductor Pollicis Canada Introduction
- 1.Anesthesiology 1989;70:237–42.Google Scholar