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Effect of Isoflurane and Sevoflurane on the Potencies of the Neuromuscular Blocking Agents in Rat in Vivo

  • Lutful Aziz
  • Yoshio Ohta
  • Nobuki Manabe
  • Hideki Nakatsuka
  • Fumiyuki Takata
  • Kiyoshi Morita
  • Masahisa Hirakawa
Conference paper

Abstract

It has been reported that Isoflurane1 and Sevoflurane2 increases the neuromuscular (NM) blocking potencies of the muscle relaxants (MR). In this study the effect of these two inhalation anesthetics at 1.25 MAC and 2.25 MAC on the potencies of vecuronium, rocuronium and the new steroidal agent SZ1676 were studied.

Keywords

Sciatic Nerve Jugular Vein Muscle Relaxant Tibialis Anterior Muscle Neuromuscular Blocking Agent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Br. J Anaesth 1984; 56: 71S-99S.Google Scholar
  2. 2.
    Masui 1988; 37: 943–954.Google Scholar
  3. 3.
    Anesthesiology 1972; 37: 573–581.Google Scholar
  4. 4.
    Anesthesiology 1984; 60: 102–105.Google Scholar

Copyright information

© Springer Japan 1955

Authors and Affiliations

  • Lutful Aziz
    • 1
  • Yoshio Ohta
    • 1
  • Nobuki Manabe
    • 1
  • Hideki Nakatsuka
    • 1
  • Fumiyuki Takata
    • 1
  • Kiyoshi Morita
    • 1
  • Masahisa Hirakawa
  1. 1.Department of Anesthesiology and ResuscitologyOkayama University Medical SchoolOkayama, 700Japan

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