Does Chronic Anticonvulsant Therapy with Carbamazepine Affect the Atracurium Induced Neuromuscular Blockade?

  • A. Spacek
  • F. X. Neiger
  • R. L. Katz
  • W. D. Watkins
  • C. K. Spiss
Conference paper


Whereas the actions of vecuronium (1), pancuronium (2) and doxacurium (3) are influenced by chronic anticonvulsant treatment with carbamazepine, neuromuscular blockade (NB) by atracurium seems to be unaffected.(4). Because of the existing controversy (5) on the influence of chronic anticonvulsant therapy on atracurium-induced NB, the present study was designed to examine the influence of carbamazepine on NB in neurosurgical patients.


Ulnar Nerve Neuromuscular Blockade Anticonvulsant Therapy Neurosurgical Procedure Neurosurgical Patient 
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  1. 1).
    Anesthesiology 67: A345, 1987Google Scholar
  2. 2).
    Anesthesiology 66: 691–693, 1987Google Scholar
  3. 3).
    Anesthesiology 71: A 785, 1989Google Scholar
  4. 4).
    Anesth Analg 67: S 550, 1988Google Scholar
  5. 5).
    Anesth Analg 71: 665–669, 1990Google Scholar

Copyright information

© Springer Japan 1995

Authors and Affiliations

  • A. Spacek
    • 1
  • F. X. Neiger
    • 2
  • R. L. Katz
    • 3
  • W. D. Watkins
    • 4
  • C. K. Spiss
    • 2
  1. 1.Departments of Anesthesia and General Intensive Care AUniversity of ViennaViennaAustria
  2. 2.Departments of Anesthesia and General Intensive Care BUniversity of ViennaViennaAustria
  3. 3.Department of AnesthesiologyUCLA School of MedicineLos AngelesUSA
  4. 4.Department of Anesthesiology, CCMUniversity of Pittsburgh Medical CenterPittsburghUSA

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