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Mivacurium-Induced Neuromuscular Blockade (NB) Is Not Affected by Chronic Anticonvulsant Therapy with Carbamazepine

  • A. Spacek
  • F. X. Neiger
  • R. L. Katz
  • W. D. Watkins
  • C. K. Spiss
Conference paper

Abstract

Patients chronically receiving carbamazepine are known to be resistant to nondepolarizing muscle relaxants: vecuronium (1), pancuronium (2) and doxacurium (3). This effect does not apply to atracurium (4). The present study was designed to investigate the influence of carbamazepine on NB of mivacurium in neurosurgical patients.

Keywords

Pulse Oximetry Neuromuscular Blockade Neurosurgical Patient Plasma Drug Level Recovery Index 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1).
    Anesthesiology 67: A345, 1987Google Scholar
  2. 2).
    Anesthesiology 66: 691–693, 1987Google Scholar
  3. 3).
    Anesthesiology 71: A 785, 1989Google Scholar
  4. 4).
    Anesth Analg 67: S 550, 1988Google Scholar

Copyright information

© Springer Japan 1995

Authors and Affiliations

  • A. Spacek
    • 1
  • F. X. Neiger
    • 2
  • R. L. Katz
    • 3
  • W. D. Watkins
    • 4
  • C. K. Spiss
    • 2
  1. 1.Departments of Anesthesia and General Intensive Care AUniversity of ViennaViennaAustria
  2. 2.Departments of Anesthesia and General Intensive Care BUniversity of ViennaViennaAustria
  3. 3.Department of AnesthesiologyUCLA School of MedicineLos AngelesUSA
  4. 4.Department of Anesthesiology, CCMUniversity of Pittsburgh Medical CenterPittsburghUSA

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