Summary
Organisms into which foreign DNA (transgene) have been artificially introduced and integrated in their genomes are called transgenic organisms. Since the mid 1980s, many species of transgenic fish have been produced by introducing desired foreign DNA into unfertilized or newly fertilized eggs by microinjection or electroporation. More recently, transgenic finfish, shellfish and crustaceans have also been produced by infecting newly fertilized eggs or the immature gonads with replication-defective pantropic retroviral vectors carrying the desired foreign DNA. These transgenic fish serve as excellent experimental models for basic scientific investigations as well as biotechnological applications. In this paper, we will review the current status of the transgenic fish technology and its potential application in producing disease resistant fish strains via manipulation of anti-microbial peptide genes.
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Chen, T.T., Sarmasik, A., Chun, C.Z., Lu, J.K., Chiou, P. (2003). Recent Advances in Transgenic Fish Technology. In: Shimizu, N., Aoki, T., Hirono, I., Takashima, F. (eds) Aquatic Genomics. Springer, Tokyo. https://doi.org/10.1007/978-4-431-65938-9_34
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DOI: https://doi.org/10.1007/978-4-431-65938-9_34
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