Selective Anodic Fluorination of Heterocycles. Potential Application towards Pharmaceuticals

  • Toshio Fuchigami


Various heterocyclic compounds having potentially biological activities were regioselectively monofluorinated by electrochemical fluorination using various supporting fluoride salts. Indirect anodic fluorodesulfurization of β-lactams using triarylamine mediators was also successful.


Heterocyclic Compound High Current Efficiency Fluoride Salt Platinum Anode Benzylic Carbon 


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Copyright information

© Springer Japan 1998

Authors and Affiliations

  • Toshio Fuchigami
    • 1
  1. 1.Department of Electronic ChemistryTokyo Institute of TechnologyNagatsuta, Yokohama 226Japan

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