Stereoselectivity in the Electroreductive Syntheses with Aryl and Alkenyl Halides Catalyzed by Nickel Complexes
The nickel-catalyzed electroreductive coupling between aryl halides and 2-chloropropionic acid derivatives bearing chiral auxiliaries leads to chiral 2-arylpropionic acids with high enantiomeric excesses. The electrochemical alkenylation of activated olefins catalyzed by nickel complexes occurs with complete transfer of the streochemistry of the starting alkenyl halide onto the product.
KeywordsNickel Complex Aryl Halide Complete Transfer Chiral Auxiliary Sacrificial Anode
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