Skip to main content
  • 96 Accesses

Abstract

Ultrasonic contrast agents with microbubbles were originally intended to make use of the difference between the acoustic impedance of gas and that of blood and tissues to obtain strong echo signals. In the case of contrast agents for intravenous administration, microbubbles must pass through the capillaries in the lungs, and therefore can be no larger than about 8 μm in diameter. Because of this limitation, the scattering intensity obtained with these microbubbles is not high enough to visualize blood flow easily by conventional B-mode imaging.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Burns PN: Harmonic imaging adds to ultrasound capabilities. Diagn Imaging 1995; AU7–AU10

    Google Scholar 

  2. Graubner T, Lazenby J, Nock LF, et al: The detection of slow flow by non-linear ultrasound imaging of contrast agents using harmonic imaging and a new phase inversion technique in vitro. Radiology 1997; 205:418

    Google Scholar 

  3. Kamiyama N, Moriyasu F, Mine Y, Goto Y: Analysis of flash echo from contrast agent for designing optimal ultrasound diagnostic systems. Ultrasound Med Biol 1998; 25:411–20

    Article  Google Scholar 

  4. Shi WT, Forsberg F, Hall AL, et al: Subharmonic imaging with microbubble contrast agents: initial results. Ultrason Imaging 1999; 21:79–94

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer Japan

About this chapter

Cite this chapter

Kudo, M. (2003). Principles of Harmonic Imaging. In: Contrast Harmonic Imaging in the Diagnosis and Treatment of Hepatic Tumors. Springer, Tokyo. https://doi.org/10.1007/978-4-431-65904-4_9

Download citation

  • DOI: https://doi.org/10.1007/978-4-431-65904-4_9

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-65906-8

  • Online ISBN: 978-4-431-65904-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics