Vascularity and Hemodynamics of Liver Tumors as Seen with Intraarterial Contrast-Enhanced Ultrasonography

  • Masatoshi Kudo


To perform contrast harmonic imaging of liver tumors and to evaluate the results correctly, one must understand tumor vascularity and hemodynamics. This chapter, therefore, describes tumor vascularity based on intraarterial contrast-enhanced ultrasonography (US), which is the gold standard for harmonic imaging.


Portal Blood Tumor Periphery Surrounding Liver Tissue Moderately Differentiate Early Stage Hepatocellular Carcinoma 
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  1. 1.
    Kudo M, Tomita S, Tochio H, et al: Small hepatocellular carcinoma: diagnosis with US angiography with intraarterial CO2 microbubbles. Radiology 1992; 182:155–160PubMedGoogle Scholar
  2. 2.
    Kudo M, Tomita S, Tochio H, et al: Sonography with intraarterial infusion of carbon dioxide microbubbles (sonographic angiography): value in differential diagnosis of hepatic tumors. AJR 1992; 158:65–74PubMedGoogle Scholar
  3. 3.
    Matsuda Y, Yabuuchi I: Hepatic tumors: US contrast enhancement with CO2 microbubbles. Radiology 1986; 161:701–705PubMedGoogle Scholar
  4. 4.
    Kudo M, Tomita S, Kashida H, et al: Tumor hemodynamics in hepatic nodules associated with liver cirrhosis: relationship between cancer progression and tumor hemodynamic change. Jpn J Gastroenterol 1991; 88:1554–1565Google Scholar
  5. 5.
    Kudo M, Tomita S, Tochio H, et al: Hemodynamic characteristics of early stage hepatocellular carcinoma: in vivo evaluation with vascular imagings. Acta Hepatol Jpn 1992; 33:283–291CrossRefGoogle Scholar
  6. 6.
    Kutami R, Nakashima Y, Nakashima O, et al: Pathomorphologic study on the mechanism of fatty change in small hepatocellular carcinoma of humans. J Hepatol 2000; 33:282–289PubMedCrossRefGoogle Scholar
  7. 7.
    Kudo M: Imaging blood flow characteristics of hepatocellular carcinoma. Oncology 2002; 62(Suppl l):48–56PubMedCrossRefGoogle Scholar
  8. 8.
    Kudo M: Imaging diagnosis of hepatocellular carcinoma and premalignant/borderline lesions. Semin Liver Dis 1999; 19:297–309PubMedCrossRefGoogle Scholar
  9. 9.
    Kudo M, Tomita S, Tochio H, et al: Hepatic focal nodular hyperplasia: specific findings at dynamic contrast-enhanced US with carbon dioxide microbubbles. Radiology 1991; 179:377–382PubMedGoogle Scholar

Copyright information

© Springer Japan 2003

Authors and Affiliations

  • Masatoshi Kudo
    • 1
  1. 1.Department of Gastroenterology and HepatologyKinki University School of MedicineOsakaJapan

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