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Thrombin-Antithrombin III Complex and D-Dimer in Neonates

Signs of Thrombin Generation During Birth

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Perinatal Thrombosis and Hemostasis

Abstract

In neonates, especially in sick neonates, signs of enhanced proteolysis are observed: (1) after birth the fibrinolytic activity is high, (2) fibrin/fibrinogen degradation products are elevated, and (3) fibrinogen is lower immediately after birth than after 3 days of life. Factor VIII activity is very high immediately after birth and activity of factor VIII is higher than factor VIII antigen suggesting activation of factor VIII [1–5].

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© 1991 Springer Japan

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Muntean, W., Danda, M., Rosegger, H. (1991). Thrombin-Antithrombin III Complex and D-Dimer in Neonates. In: Suzuki, S., Hathaway, W.E., Bonnar, J., Sutor, A.H. (eds) Perinatal Thrombosis and Hemostasis. Springer, Tokyo. https://doi.org/10.1007/978-4-431-65871-9_7

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  • DOI: https://doi.org/10.1007/978-4-431-65871-9_7

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-65873-3

  • Online ISBN: 978-4-431-65871-9

  • eBook Packages: Springer Book Archive

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