Abstract
Alpha-1-antitrypsin (alpha-1-AT), or alpha-1-protease inhibitor is a glycoprotein with a molecular weight of about 52. 000 daltons. More than 90% of it is synthesized by the liver. The concentration in serum in healthy children is 2.0–3.3 g/1. Alpha-1-AT constitutes about 90% of the whole alpha-1-globulin fraction. The gene responsible for the production of alpha-1-AT is situated on the long arm of chromosome 14.
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© 1991 Springer Japan
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Auerswald, G., Sutor, A.H. (1991). Six Cases of Alpha-1-Antitrypsin Deficiency Presenting as a Bleeding Diathesis with Intracranial Hemorrhage in the Newborn. In: Suzuki, S., Hathaway, W.E., Bonnar, J., Sutor, A.H. (eds) Perinatal Thrombosis and Hemostasis. Springer, Tokyo. https://doi.org/10.1007/978-4-431-65871-9_32
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DOI: https://doi.org/10.1007/978-4-431-65871-9_32
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-65873-3
Online ISBN: 978-4-431-65871-9
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