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Time Interval Between Vitamin K Administration and Effective Hemostasis

  • Antoh H. Sutor
  • Wilhelm Künzer

Abstract

In adults with vitamin K deficiency, correction of abnormal coagulation tests with vitamin K therapy cannot be expected for several hours; therefore, bleeding patients are given plasma concentrates to bridge the time before vitamin K becomes effective [1,2]. In newborns a time gap of several hours, in some instances up to 12 h, is reported [3,4]. The aim of the present study is to investigate the time interval between administration of vitamin K and, first, a significant increase of the PT value (in %) and, second, a demonstrable hemostatic effect to reverse the vitamin K deficiency bleeding with administration of vitamin K.

Keywords

Prothrombin Time Biliary Atresia Prothrombin Complex Concentrate Hemostatic Effect Intravenous Vitamin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Japan 1991

Authors and Affiliations

  • Antoh H. Sutor
    • 1
  • Wilhelm Künzer
    • 1
  1. 1.Universitäts-KinderklinikFreiburgFederal Republic of Germany

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