The Role of Hemostasis in Neonatal Intracranial Hemorrhage
The causes of intracranial hemorrhage in the newborn infant include congenital bleeding disorders (hemophilia), thrombocytopenia, disseminated intravascular coagulation (DIC), asphyxia, infection, trauma, hemorrhagic disease of the newborn (vitamin K deficiency), and those of unknown etiology. The last category occurs primarily in the premature infant and is usually termed subependymal hemorrhage-intraventricular hemorrhage (SEH-IVH). The role of hemostatic defects in IVH has been reviewed previously by Hathaway and Bonnar [1,2]. The purpose of this communication is to review and update these discussions and to emphasize an hypothesis relating abnormal hemostasis to the etiology of neonatal IVH.
KeywordsDisseminate Intravascular Coagulation Tranexamic Acid Disseminate Intravascular Coagulation Intraventricular Hemorrhage Hemorrhagic Disease
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