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Absorption, Metabolism, and Storage of K Vitamins in the Newborn

  • Martin J. Shearer
Conference paper

Abstract

The fetal and neonatal physiology and biochemistry of vitamin K is probably the least understood of all the fat-soluble vitamins. Major questions surround the transplacental transfer, intestinal absorption, intermediary metabolism, plasma transport, bioavailability, storage, and turnover of the K vitamins. Such questions include the relative importance to fetal and neonatal requirements of phylloquinone (vitamin K1), the plant synthesized form of vitamin K, and the menaquinones (vitamin K2), which are of bacterial origin. For example, the establishment of an intestinal flora which synthesize menaquinones is known to occur in the first few days of life, but the role of enteric menaquinones as a potential source of vitamin K in neonates remains as controversial a question as it does in adults.

Keywords

Bile Salt Mixed Micelle Exocrine Pancreatic Insufficiency Cord Plasma Liver Store 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Japan 1991

Authors and Affiliations

  • Martin J. Shearer
    • 1
  1. 1.Haematology Research Laboratory, Clinical Science Laboratories, Guys Tower (18th Floor)Guys HospitalLondonUK

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