Perinatal Problems of Thrombosis and Haemostasis
Prevention and treatment of deep vein thrombosis during pregnancy presents special problems. The benefit of treatment for the original condition must be weighed against the subsequent risk of placental or fetal haemorrhage. Owing to the high risk of recurrence, prophylactic treatment is required throughout pregnancy, during delivery, and in the puerperium. At an early stage of pregnancy, the risk ot teratogenetic effects needs also to be taken into consideration.
KeywordsDeep Vein Thrombosis Tranexamic Acid Acute Pulmonary Embolism Hemorrhagic Complication Fibrinolytic System
Unable to display preview. Download preview PDF.
- 4.Forestier F, Daffos F, Rainaut M, Toulemonde F (1987) Low molecular weight Heparin (CY 216) does not cross the placenta during the third trimester of pregnancy. Thromb Hemost 57: 234Google Scholar
- 9.Hall GJ (1967) Warfarin and fetal abnormality. Lancet 1: 1127Google Scholar
- 11.DiSaia PJ (1966) Pregnancy and delivery of a patient with a Starr-Edwards mitral valve prosthesis. Obstet Gynecol 28: 469–472Google Scholar
- 21.von Syndow G (1947) Hypoprothrombinemia and cerebral injury in infant after dicumarol treatment of mother. Nord Med 34: 1171–1172Google Scholar
- 22.Sach JJ, Labate JS (1949) Dicumarol in the treatment of antenatal thrombo-embolic disease: Report of a case with hemorrhagic manifestations in the fetus. Am J Obstet Gynecol 57: 965–971Google Scholar
- 27.Crawford JS (1978) Principles and practice of obstetrics anesthesia, 4th edn. Black-well Scientific Publications, Oxford, pp 182–183Google Scholar
- 37.Åstedt B (1988) Hemorrhagic diathesis due to pathological proteolysis. In: Renck H (ed) Bleeding and thrombotic disorders in the surgical patient. Appleton & Lange, Norwalk, pp 53–59Google Scholar