Skip to main content
SpringerLink
Log in

Bio- and Chemical Sensors and Role of Soft Interface

  • Chapter
  • First Online:
Molecular Soft-Interface Science

  • 495 Accesses

Abstract

The methodology of the evaluation of surface materials, surface modification layers, and sensing methods for bio/chemical molecules detection is described. In this chapter, the most important, widely used, highly sensitive, and user-friendly sensing methods for surface evaluation technology are introduced. Surface plasmon resonance measurement (SPR), quartz crystal microbalance (QCM), electrochemical measurement (cyclic voltammetry (CV) and others), the field-effect transistor (FET) method, and other methods for evaluating molecular affinities and detecting limited target molecules are taken up and role of soft interface for bio- and chemical sensors is reviewed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Marx KA (2003) Quartz Crystal microbalance: a useful tool for studying thin polymer films and complex biomolecular systems at the solution-surface interface. Biomacromolecules 4:1099–1120, and references are therein

    Article  CAS  Google Scholar 

  2. Dahlin AB, Jønsson PM, Schmid E, Zhou Y, Hook F (2008) Synchronized quartz crystal microbalance and Nanoplasmonic sensing of biomolecular recognition reactions. ACS Nano 2:2174–2182

    Article  CAS  Google Scholar 

  3. Muller MT, Yan X, Lee S, Perry SS, Spencer ND (2005) Lubrication properties of a brushlike copolymer as a function of the amount of solvent absorbed within the brush. Macromolecules 38:5706–5713

    Article  Google Scholar 

  4. Irwin EF, Ho JE, Kane SR, Healy KE (2005) Analysis of interpenetrating polymer networks via quartz crystal microbalance with dissipation monitoring. Langmuir 21:5529–5536

    Article  CAS  Google Scholar 

  5. Bonroy K, Friedt JM, Frederix F, Laureyn W, Langerock S, Campitelli A, Sara M, Borghs G, Goddeeris B, Declerck P (2004) Realization and characterization of porous gold for increased protein coverage on acoustic sensors. Anal Chem 76:4299–4306

    Article  CAS  Google Scholar 

  6. Fogel R, Mashazi P, Nyokong T, Limson J (2007) Critical assessment of the quarts crystal microbalance with dissipation as an analytical tool for biosensor development and fundamental studies: metallophthalocyanine-glucose oxidase biocomposit sensors. Biosens Bioelectron 23:95–101

    Article  CAS  Google Scholar 

  7. Shimazu K, Yagi I, Sato Y, Uosaki K (1992) In situ and dynamic monitoring of the self-assembling and redox processes of a ferrocenylundecanethiol monolayer by electrochemical quarts crystal microbalance. Langmuir 8:1385–1387

    Article  CAS  Google Scholar 

  8. Shimazu K, Sato Y, Yagi I, Uosaki K (1994) Packing state and stability of self-assembled monolayers of 11-Ferrocenyl-1-undecanethiol on platinum electrodes. Bull Chem Soc Jpn 67:863–865

    Article  CAS  Google Scholar 

  9. Shimazu K, Ye S, Sato Y, Uosaki K (1994) Simultaneous detection of structural change and mass transport accompanying the redox of a ferrocenylundecanethiol monolayer with the novel ft-ir reflection adsorption spectroscopy/electrochemical quartz crystal microbalance combined system. J Electroanal Chem 375:409–413

    Article  CAS  Google Scholar 

  10. Sato Y, Mizutani F, Shimazu K, Ye S, Uosaki K (1997) Mass transport accompanied with electron transfer between the gold electrode modified with 11-Ferrocenylundecanethiol monolayer and redox species in solution—an electrochemical quartz crystal microbalance study. J Electroanal Chem 434:115–119

    Article  CAS  Google Scholar 

  11. Homola J (2008) Surface plasmon resonance sensors for detection of chemical and biochemical species. Chem Rev 108:462–493 and references therein

    Article  CAS  Google Scholar 

  12. Iwasaki Y, Horiuchi T, Niwa O (2001) Detection of electrochemical enzymatic reactions by surface plasmon resonance measurement. Anal Chem 73:1595–1598

    Article  CAS  Google Scholar 

  13. Bin Y, Fu Q, Hou Y, Xiang J (2013) Real-time composition and deposition depth profile of metal alloys using electrochemical surface plasmon resonance. J Electroanal Chem 699:10–13

    Article  CAS  Google Scholar 

  14. Walczak MM, Popenoe DD, Deinhammer RS, Lamp BD, Chung C, Porter MD (1991) Reductive desorption of alkanethiolate monolayers at gold: a measure of surface coverage. Langmuir 7:2687–2693

    Article  CAS  Google Scholar 

  15. Weisshaar DE, Walczak MM, Porter MD (1993) Electrochemically induced transformations of monolayers formed by self-assembly of mercaptoethanol at gold. Langmuir 9:323–329

    Article  CAS  Google Scholar 

  16. Widrig CA, Chung C, Porter MD (1991) The electrochemical desorption of n-alkanethiol monolayers from polycrystalline gold and silver electrodes. J Electroanal Chem 310:335–359

    Article  CAS  Google Scholar 

  17. Sato Y, Mizutani F (2000) Electrochemical responses of cytochrome c on gold electrodes modified with nucleic acid base electrochimica acta 45:2869–2875

    CAS  Google Scholar 

  18. Sato Y, Ishikawa Y, Matsuura H, Uosaki K, Mizutani F, Niwa O (2005) Highly-sensitive detection of 6-mercaptopurine and its metabolites by electrochemical reductive desorption measurements. Electroanalysis 17:965–968

    Article  CAS  Google Scholar 

  19. Imabayashi SI, Hobara D, Kakiuchi T (2001) Voltammetric detection of the surface diffusion of adsorbed thiolate molecules in artificially phase-separated binary self-assembled monolayers on a Au(111) surface. Langmuir 17:2560–2563

    Article  CAS  Google Scholar 

  20. Hobara D, Ota M, Imabayashi SI, Niki K, Kakiuchi T (1998) Phase separation of binary self-assembled thiol monolayers composed of 1-Hexadecanethiol and 3-Mercaptopropionic Acid on Au(111) studies by scanning tunnering microscopy and cyclic voltammetry. J Electroanal Chem 444:113–119

    Article  CAS  Google Scholar 

  21. Sato Y, Niwa O, Mizutani F (2007) Hydrogen bonding interaction between aminopurinethiol-monolayers and oligonucleotides by QCM and XPS measurements. Sensors Actuators B 121:214–218

    Article  CAS  Google Scholar 

  22. Shi H, Song Z, Huang J, Yang Y, Zhao Z, Anzai JI, Osa T, Chen Q (2005) Effects of the type of polycation in the coating films prepared by a Layer-by-Layer desorption technique on the properties of amperometric choline sensors. Sens Actuators B 109:341–347

    Article  CAS  Google Scholar 

  23. Sato Y, Yoshioka K, Tanaka M, Murakami T, Ishida NM, Niwa O (2008) Recognition of lectin with a high signal to noise ratio: carbohydrate-tri(ethylene glycol)-Alkanethiol Co-adsorbed monolayer. Chem Commun 4909–4911

    Google Scholar 

  24. Yoshioka K, Sato Y, Tanaka M, Murakami T, Niwa O (2010) Suppression of non-specific adsorption using densified tri(ethylene glycol) alkanethiols: monolayer characteristics evaluated by electrochemical measurements. Anal Sci 26:33–37

    Article  CAS  Google Scholar 

  25. Joo S, Brown RB (2008) Chemical sensors its integrated electronics. Chem Rev 108:638–651

    Article  CAS  Google Scholar 

  26. Schoning MJ, Poghossian A (2002) Recent advances in biologically sensitive field-effect transistors. Analyst 127:1137–1151 and references therein

    Article  Google Scholar 

  27. Yumusak C, Singh TB, Sariciftci NS, Grote JG (2009) Bio-organic field effect transistors based on Crosslinked deoxyribonucleic Acid (DNA) gate dielectric app. Phys Lett 95:2633034

    Google Scholar 

  28. Goda T, Miyahara Y (2012) Interpretation of protein adsorption through its intrinsic electric charges: a comparative study using a field-effect transistor, surface plasmon resonance, and quartz crystal microbalance. Langmuir 28:14730–14738

    Article  CAS  Google Scholar 

  29. Kim A, Ah CS, Park CW, Yang JH, Kim T, Ahn CG, Park SH, Sung GY (2010) Direct label-free electrical immunodetection in human serum using a flow-through-apparatus approach with integrated field-effect transistors. Biosens Bioelectron 25:1767–1773

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Umezono, Tsukuba, Ibaraki, 305-8560, Japan

    Yukari Sato

Authors
  1. Yukari Sato
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yukari Sato .

Editor information

Editors and Affiliations

  1. RIKEN, Wako, Japan

    Mizuo Maeda

  2. Kyushu University, Fukuoka, Japan

    Atsushi Takahara

  3. Toyama University, Toyama, Japan

    Hiromi Kitano

  4. National Cerebral and Cardiovascular Cen, Suita, Japan

    Tetsuji Yamaoka

  5. Kyushu University, Fukuoka, Japan

    Yoshiko Miura

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Japan KK, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Sato, Y. (2019). Bio- and Chemical Sensors and Role of Soft Interface. In: Maeda, M., Takahara, A., Kitano, H., Yamaoka, T., Miura, Y. (eds) Molecular Soft-Interface Science. Springer, Tokyo. https://doi.org/10.1007/978-4-431-56877-3_13

Download citation

Publish with us

Policies and ethics

Search

Navigation