Skip to main content
SpringerLink
Log in

Physical Properties of Biomembranes and Cellular Functions

  • Chapter
  • First Online:
Physical Principles of Biomembranes and Cells

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

  • 757 Accesses

Abstract

Membrane lipids such as phospholipids, glycolipids and sterols form lipid bilayer membranes spontaneously in water, and insertion and binding of proteins result in construction of biomembranes. Membrane proteins are surrounded by lipid molecules, and structure and physical properties of lipid membrane regulate function and activity of protein through interaction between lipids and proteins. Biological functions on biomembranes utilize physical property of lipid bilayer membranes. Molecular collision for chemical reaction is controlled by membrane fluidity which depends on lipid species of different structures such as length and unsaturation. Special regions for signaling system on cell membrane are formed by phase separation. Membrane lipid preferring non -bilayer forming is closely related to membrane fusion.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. D. Axelrod, D.E. Koppel, J. Schlessinger, E. Elson, W.W. Webb, Biophys. J. 16, 1055 (1976)

    Article  ADS  Google Scholar 

  2. E. Hanski, G. Rimon, A. Levitzki, Biochemistry 18, 846 (1979)

    Article  Google Scholar 

  3. S. Ohnishi, T. Ito, Biochemistry 13, 88116 (1974)

    Article  Google Scholar 

  4. J.M. Boggs, D.D. Wood, M.A. Moscarello, D. Papahadjopoulos, Biochemistry 16, 2325 (1977)

    Article  Google Scholar 

  5. S. Tokutomi, K. Ohki, S. Ohnishi, Biochim. Biophys. Acta 596, 192 (1980)

    Article  Google Scholar 

  6. K. Ohki, K. Takahashi, S. Kato, A. Maesono, Chem. Phys. Lipids 50, 109 (1989)

    Article  Google Scholar 

  7. K. Ohki, T. Yamauchi, Y. Banno, Y. Nozawa, Biochem. Biophys. Res. Commun. 100, 321 (1981)

    Article  Google Scholar 

  8. K. Simons, E. Ikonrn, Nature 387, 569 (1997)

    Article  ADS  Google Scholar 

  9. D.A. Brown, E. London, Annu. Rev. Cell Dev. Biol. 14, 111 (1981)

    Article  Google Scholar 

  10. J.H. Ipsen, O.G. Mouritsen, Biochim. Biophys. Acta 944,121 (1988)

    Google Scholar 

  11. J.R. Silvius, Biochim. Biophys. Acta 1610, 174 (2003)

    Article  Google Scholar 

  12. W. Guo, V. Kuze, T. Huber, N.H. Afdal, K. Beyer, J.A. Hamilton, Biophys. J. 83, 1465 (2002)

    Article  ADS  Google Scholar 

  13. K. Ohki, J. Phys. Condens. Matter 17, S2957 (2005)

    Article  ADS  Google Scholar 

  14. Y. Taniguchi, T. Ohba, H. Miyata, K. Ohki, Biochm. Biophys. Acta 1758, 145 (2006)

    Article  Google Scholar 

  15. M.R. de Planque, E. Goormaghtigh, D.V. Greathouse, R.E. Koeppe 2nd, J.A. Kruijtzer, R.M. Liskamp, B. de Kruijff, J. Killian, Biochemistry 40, 5000 (2001)

    Article  Google Scholar 

  16. A. Kishimoto, Y. Takai, T. Mori, U. Kikkawa, Y. Nishizuka, J. Biol. Chem. 25, 2273 (1983)

    Google Scholar 

  17. D.S. Drust, T.F.F. Martin, Biochem. Biopys. Res. Commun. 128, 531 (1985)

    Article  Google Scholar 

  18. E. Melloni, S. Pontrmoli, M. Michetti, O. Sacco, B. Sparatore, F. Salamino, B.L. Horecker, Proc. Natl. Acad. Sci. USA, vol 82 (1985), p. 6435

    Google Scholar 

  19. K. Ohki, T. Sekiya, T. Yamauchi, Y. Nozawa, Biochim. Biophys. Acta 693, 341 (1982)

    Article  Google Scholar 

  20. R. Charest, P.F. Blackmore, B. Berthon, J.H. Exton, J. Biol. Chem. 258, 8769 (1983)

    Google Scholar 

  21. M.A.D. Bazzi, G.L. Nelsestuen, Biochemistry 27, 6776 (1988)

    Article  Google Scholar 

  22. P.J. Parker, L. Coussens, N. Totty, L. Rhee, S. Young, E. Chen, S. Stabel, M.D. Waterfield, A. Ullrich, Science 233, 853 (1986)

    Article  ADS  Google Scholar 

  23. C. House, B. Kemp, Science 238, 1726 (1987)

    Article  ADS  Google Scholar 

  24. M. Makowske, O.M. Rosen, J. Biol. Chem. 264, 16155 (1989)

    Google Scholar 

  25. M. Mosior, S. McLaughlin, Biophys. J. 60, 149 (1991)

    Article  Google Scholar 

  26. F. Sakane, K. Yamada, S. Imai, H. Kanoh, J. Biol. Chem. 266, 7096 (1991)

    Google Scholar 

  27. C.B. Klee, Biochemistry 27, 6645 (1988)

    Article  Google Scholar 

  28. M.D. Bazzi, G.L. Nelsestuen, Biochemistry 30, 7961 (1991)

    Article  Google Scholar 

  29. L. Yang, M. Glaser, Biochemist 34, 1500 (1995)

    Article  Google Scholar 

  30. P.R. Cullis, B. de Kruijff, Biochim. Biophys. Acta 507, 207–218 (1978)

    Article  Google Scholar 

  31. K. Ohki, S. Nagaoka, M. Sogami, Y. Nozawa, Chem. Phys. Lipids 39, 237 (1986)

    Article  Google Scholar 

  32. S.J. Singer, G.L. Nicolson, Science 175, 720 (1972)

    Article  ADS  Google Scholar 

  33. A.J. Verkleij, C. Mombers, J. Leunissen-Bijvelt, P.H.J.T. Ververgaert, Nature 279, 162 (1978)

    Article  Google Scholar 

  34. J.N. Israelachvili, D.J. Mitchell, B.W. Ninham, Biochim. Biophys. Acta 470, 185 (1977)

    Article  Google Scholar 

  35. P. Hanson, R. Roth, H. Morisaki, R. Jahn, J.E. Hauser, et al. Cell 90, 523–535 (1997)

    Article  Google Scholar 

  36. R.B. Sutton, D. Fasshause, R. Jahn, A.T. Brunger, Nature 395, 347 (1998)

    Article  ADS  Google Scholar 

  37. Y. Higashino, A. Matsui, K. Ohki, J. Biochem. (Japan) 130, 393 (2001)

    Article  Google Scholar 

  38. P.M. Frederik, M.C.A. Stuart, A.J. Verkleij, Biochim. Biophys. Acta 979, 275 (1989)

    Article  Google Scholar 

  39. P.R. Cullis, B. de Kruijff, Biochim. Biophys. Acta 559(1979), 399 (1979)

    Article  Google Scholar 

  40. H. Ellens, D.P. Siegel, D. Alford, P.L. Yeagle, L. Boni, L.J. Lis, P.J. Quinn, J. Bentz, Biochemistry 28, 3692 (1989)

    Article  Google Scholar 

  41. M. Paz Sanchez-Milgalon, F.J. Aranda, J.C. Gomez-Fernandez, Biophys. J. 68, 558 (1995)

    Article  Google Scholar 

  42. U.-L. Nieva, F.M. Goni, A. Alonso, Biochemistry 28, 7364 (1989)

    Article  Google Scholar 

  43. G. Garab, K. Lohner, P. Laggner, T. Farkas, Trends Plant Sci. 5, 489 (2000)

    Article  Google Scholar 

  44. H. Takahashi, M. Watanabe, P.J. Quinn, S. Kato, S. Murayama, K. Ohki, I. Hatta, Biophys. Chem. 77, 37 (1999)

    Article  Google Scholar 

  45. B. de Kruijff, Nature 386, 129 (1977)

    Article  Google Scholar 

  46. C. Van der Does, J. Swaving, W. van Klompenberg, A.J. Driessen, J. Biol. Chem. 275, 2472 (2000)

    Article  Google Scholar 

  47. X. Zha, L.M. Pierini, P.L. Leopold, P.J. Skiba, I. Tabas, F.R. Maxfield, J. Cell Biol. 140, 39 (1998)

    Article  Google Scholar 

  48. R.F. Epand, J.-C. Martinou, M. Fornallaz-Mulhauser, D.W. Hughes, R.M. Epand, J. Biol. Chem. 277, 32632 (2002)

    Article  Google Scholar 

  49. P.G. de Gennes, The Physics of Liquid Crystals (Oxford University Press, London, 1974)

    MATH  Google Scholar 

  50. L. Miao, U. Seifert, M. Wortis, H.G. Dobereiner, Phys. Rev. E 49, 5389 (1997)

    Article  ADS  Google Scholar 

  51. G. Cevec, D. Marsh, Phospholipid Bilayers (Wiley, New York, 1987)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physics, Tohoku University, Sendai, Japan

    Kazuo Ohki & Hidetake Miyata

Authors
  1. Kazuo Ohki
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hidetake Miyata
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer Japan KK, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Ohki, K., Miyata, H. (2018). Physical Properties of Biomembranes and Cellular Functions. In: Physical Principles of Biomembranes and Cells. Biological and Medical Physics, Biomedical Engineering. Springer, Tokyo. https://doi.org/10.1007/978-4-431-56841-4_6

Download citation

Publish with us

Policies and ethics

Search

Navigation