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Homeostasis of Free d-Aspartate in Mammalian Cells

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Abstract

Among the free d-amino acids found in mammals, d-aspartate (d-Asp) has been shown to play crucial roles in the central nervous, neuroendocrine, and endocrine systems. Here, we present an overview of recent studies on free d-Asp, focusing on homeostasis in mammalian cells, especially the molecular mechanisms necessary to synthesize, degrade, and release d-Asp.

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Authors and Affiliations

  1. Laboratory of Biomolecular Science, Graduate School of Pharmaceutical Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan

    Hiroshi Homma & Masumi Katane

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  1. Hiroshi Homma
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  2. Masumi Katane
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Correspondence to Hiroshi Homma .

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  1. Department of Applied Molecular Biosciences Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan

    Tohru Yoshimura

  2. Department of Psychiatry and Behavioral Sciences Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

    Toru Nishikawa

  3. Laboratory of Biomolecular Science Department of Pharmaceutical Life Sciences, Kitasato University, Tokyo, Japan

    Hiroshi Homma

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Homma, H., Katane, M. (2016). Homeostasis of Free d-Aspartate in Mammalian Cells. In: Yoshimura, T., Nishikawa, T., Homma, H. (eds) D-Amino Acids. Springer, Tokyo. https://doi.org/10.1007/978-4-431-56077-7_13

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