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Pregnancy and Delivery

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Aortopathy

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Abstract

Exposure of estrogen and hemodynamic changes during pregnancy lead to the fragility of the elastic fiber of the aortic media. It elevates the risk for aortic dilatation and dissection. We observe cystic medial necrosis change in the aortic wall media during pregnancy, and the diameter of the aorta increases slightly. This phenomenon generally called aortopathy is especially important in the management of connective tissue diseases such as Marfan syndrome patients during pregnancy.

A large sinus of Valsalva, increased aortic size index, and rapid growth of the sinus of Valsalva are risk factors for aortic dilatation or dissection in pregnant women with Marfan syndrome.

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Author information

Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, Tokyo, 183-0003, Japan

    Shinji Katsuragi M.D.

  2. Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center, Osaka, Japan

    Jun Yoshimatsu

  3. Department of Cardiology, St. Luke’s International Hospital, Tokyo, Japan

    Koichiro Niwa

  4. Department of Obstetrics and Gynecology, Mie University, Tsu, Mie, Japan

    Tomoaki Ikeda

Authors
  1. Shinji Katsuragi M.D.
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  2. Jun Yoshimatsu
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  3. Koichiro Niwa
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  4. Tomoaki Ikeda
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Corresponding author

Correspondence to Shinji Katsuragi M.D. .

Editor information

Editors and Affiliations

  1. Cardiovascular Center, St Luke’s International Hospital, Chuo-ku, Tokyo, Japan

    Koichiro Niwa

  2. ACHD Unit, German Heart Centre Munich, Munich, Bayern, Germany

    Harald Kaemmerer

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Katsuragi, S., Yoshimatsu, J., Niwa, K., Ikeda, T. (2017). Pregnancy and Delivery. In: Niwa, K., Kaemmerer, H. (eds) Aortopathy. Springer, Tokyo. https://doi.org/10.1007/978-4-431-56071-5_9

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  • DOI: https://doi.org/10.1007/978-4-431-56071-5_9

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  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-56069-2

  • Online ISBN: 978-4-431-56071-5

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