Various Atypical Cadherins: T-Cadherin, RET, Calsyntenin, and 7D-Cadherin

  • Keiko Imai-Okano
  • Shinji HiranoEmail author


In addition to the various cadherins described in previous chapters, there are several atypical cadherins that have unique structures and functions. Because of their great diversity, some cadherins have unexpected roles beyond cell–cell adhesion. In this chapter, we review interesting features of T-cadherin, RET, calsyntenins, and 7D-cadherins that have been discovered in the past 20 years.


T-cadherin 7D-cadherin LI-cadherin Ksp-cadherin Cadherin-13 Cadherin-16 Cadherin-17 RET Calsyntenin Alcadein 



We often cited review articles as references for simplicity and due to space limitations, and we are sorry for any omissions of original works from the references. We thank Drs. Lawrence Shapiro, Neil Q. McDonald, and Gabrielle Rudenko for their generous permissions to reproduce their original figures. This work was supported by grants from and the Kansai Medical University Project for Young Researchers (to K.I.), the JSPS KAKENHI Grant Number 25430037, RIKEN cooperative research, Takeda Science Foundation, Sumitomo Foundation, and MEXT-Supported Program for the Strategic Research Foundation at Private Universities (S1201038) (to S. H.).


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Copyright information

© Springer Japan 2016

Authors and Affiliations

  1. 1.Department of Cell BiologyKansai Medical UniversityHirakataJapan

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