Whole-Body Matter

  • Yoshiro Maru


In 1786, John Hunter observed pulmonary lesions as a metastatic manifestation from a tumorous disease in the femoral bone, which turned out to be a rare disease: osteosarcoma (see Table  9.1 in Chap.  9). This raised the curtain on metastatic diseases. The disease spreads from the leg to the chest as a whole-body matter. Here I will discuss cancer from the standpoint of inflammation, which is basically a whole-body matter with inevitable immunological reactions.


Mast Cell Lung Metastasis White Adipose Tissue Circulate Tumor Cell Lewis Lung Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Japan 2016

Authors and Affiliations

  • Yoshiro Maru
    • 1
  1. 1.Department of PharmacologyTokyo Women’s Medical UniversityTokyoJapan

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