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Difficulty in Diagnosing Inflammatory Bowel Disease: A Case Study

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Abstract

Endoscopy is an important tool for diagnosing inflammatory bowel disease (IBD). It is well known that various types of infectious colitis, such as tuberculosis, mimic Crohn’s disease (CD). A broad differential diagnosis is important because IBD is a diagnosis of exclusion. On the other hand, some cases need different viewpoints in order to make the correct diagnosis. Here we present cases where the diagnoses were elusive. The first case was a very early case of ulcerative colitis (UC). The lesions did not show a typical distribution for UC. However, eventually, typical symptoms and endoscopic appearance were observed, confirming the diagnosis. The second case revealed lesions only in the upper jejunum. Capsule endoscopy and balloon-assisted enteroscopy revealed the typical appearance of CD; however, the distribution of the lesions was not typical. It took a long time to make the diagnosis. The third case involved recurrent obstruction. Mucosal healing was achieved; however, stenosis of the ileocecal valve resulted in surgery. Concomitant use of NSAIDs induced membranous stenosis, and therefore, endoscopic balloon dilation was performed.

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References

  1. Epstein D, Watermeyer G, Kirsch R. Review article: the diagnosis and management of Crohn's disease in populations with high-risk rates for tuberculosis. Aliment Pharmacol Ther. 2007;25:1373–88.

    Article  CAS  PubMed  Google Scholar 

  2. Katsanos KH, Voulgari PV, Tsianos EV. Inflammatory bowel disease and lupus: a systematic review of the literature. J Crohns Colitis. 2012;6:735–42.

    Article  PubMed  Google Scholar 

  3. Leighton JA, Shen B, Baron TH, et al. ASGE guideline: endoscopy in the diagnosis and treatment of inflammatory bowel disease. Gastrointest Endosc. 2006;63:558–65.

    Article  PubMed  Google Scholar 

  4. Burgmann T, Clara I, Graf L, et al. The Manitoba Inflammatory Bowel Disease Cohort Study: prolonged symptoms before diagnosis—how much is irritable bowel syndrome? Clin Gastroenterol Hepatol. 2006;4:614–20.

    Article  PubMed  Google Scholar 

  5. Geboes K, Ectors N, D'Haens G, et al. Is ileoscopy with biopsy worthwhile in patients presenting with symptoms of inflammatory bowel disease? Am J Gastroenterol. 1998;93:201–6.

    Article  CAS  PubMed  Google Scholar 

  6. Lazarev M, Huang C, Bitton A, et al. Relationship between proximal Crohn's disease location and disease behavior and surgery: a cross-sectional study of the IBD Genetics Consortium. Am J Gastroenterol. 2013;108:106–12.

    Article  CAS  PubMed  Google Scholar 

  7. Cheifetz AS, Lewis BS. Capsule endoscopy retention: is it a complication? J Clin Gastroenterol. 2006;40:688–91.

    Article  PubMed  Google Scholar 

  8. Tanaka S, Mitsui K, Shirakawa K, et al. Successful retrieval of video capsule endoscopy retained at ileal stenosis of Crohn's disease using double-balloon endoscopy. J Gastroenterol Hepatol. 2006;21:922–3.

    Article  PubMed  Google Scholar 

  9. Nakamura M, Hirooka Y, Yamamura T, et al. Clinical usefulness of novel tag-less Agile patency capsule prior to capsule endoscopy for patients with suspected small bowel stenosis. Dig Endosc. 2015;27:61–6.

    Article  PubMed  Google Scholar 

  10. Pariente B, Cosnes J, Danese S, et al. Development of the Crohn's disease digestive damage score, the Lémann score. Inflamm Bowel Dis. 2011;17:1415–22.

    Article  PubMed  Google Scholar 

  11. Wang ML, Miao F, Tang YH, et al. Special diaphragm-like strictures of small bowel unrelated to non-steroidal anti-inflammatory drugs. World J Gastroenterol. 2011;17:3596–604.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Takenaka K, Ohtsuka K, Kitazume Y, et al. Comparison of magnetic resonance and balloon enteroscopic examination of the small intestine in patients with Crohn's disease. Gastroenterology. 2014;147:334–42.

    Article  PubMed  Google Scholar 

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Correspondence to Kazuo Ohtsuka .

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Ohtsuka, K. (2018). Difficulty in Diagnosing Inflammatory Bowel Disease: A Case Study. In: Hibi, T., Hisamatsu, T., Kobayashi, T. (eds) Advances in Endoscopy in Inflammatory Bowel Disease. Springer, Tokyo. https://doi.org/10.1007/978-4-431-56018-0_14

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  • DOI: https://doi.org/10.1007/978-4-431-56018-0_14

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  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-56016-6

  • Online ISBN: 978-4-431-56018-0

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