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Lymphatic Mapping and Optimization of Sentinel Lymph Node Dissection

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Personalized Treatment of Breast Cancer

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Abstract

Sentinel lymph node (SLN) biopsy is a standard of care for axillary staging in breast cancer. The modalities involving radioisotope (RI) and blue dye are the most widely used for SLN mapping. Near-infrared fluorescence imaging using indocyanine green (ICG) visualizes superficial lymphatic flow from tumor to SLN transcutaneously and directs the surgeon to the tumor-draining SLN in the axillary basin. This novel method achieves a high detection of SLN comparable with the RI method, and the additional use of ICG fluorescence maximizes the detection impact of RI. The ICG fluorescence method is reliable and safe and would be an acceptable alternative to SLN mapping using radioactive tracers in early breast cancer.

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Authors and Affiliations

  1. Department Surgery, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka, 573-1191, Japan

    Tomoharu Sugie

  2. Faculty of Health Care, Tenri Health Care University, Nara, Japan

    Takashi Inamoto

Authors
  1. Tomoharu Sugie
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  2. Takashi Inamoto
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Correspondence to Tomoharu Sugie .

Editor information

Editors and Affiliations

  1. Department of Breast Surgery Graduate Sc, Kyoto University, Kyoto, Kyoto, Japan

    Masakazu Toi

  2. Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA

    Eric Winer

  3. Addenbrooke’s Hospital, Cambridge University Hospitals, Cambridge, Cambridgeshire, United Kingdom

    John Benson

  4. University of Arkansas for Medical Scien, Little Rock, Arkansas, USA

    Suzanne Klimberg

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© 2016 Springer Japan

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Sugie, T., Inamoto, T. (2016). Lymphatic Mapping and Optimization of Sentinel Lymph Node Dissection. In: Toi, M., Winer, E., Benson, J., Klimberg, S. (eds) Personalized Treatment of Breast Cancer. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55552-0_9

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  • DOI: https://doi.org/10.1007/978-4-431-55552-0_9

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  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-55551-3

  • Online ISBN: 978-4-431-55552-0

  • eBook Packages: MedicineMedicine (R0)

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