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Dye-Staining Coronary Angioscopy and Cardioscopy

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Coronary Angioscopy

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Abstract

Coronary angioscopy or cardioscopy using biocompatible markers is one choice for evaluation of tissues, cells, or molecules which comprise the target lesions. Angioscopy using EB as a biomarker, namely, dye-staining angioscopy, has been developed and applied for molecular imaging of the substances that constitute atherosclerotic lesions.

By dye-staining angioscopy, coronary endothelial damage can be visualized. This technique could also provide discrimination of coronary fibrin from platelets and visualization of transparent fibrin thrombi, namely, a structure that was not visible by conventional angioscopy in patients with acute coronary syndrome (ACS). Fluffy coronary luminal surface without significant stenosis nor obstructive thrombus can be observed in patients with ACS.

Following percutaneous coronary intervention, this dye-staining angioscopy could detect damaged endothelial cells on coronary stent struts in chronic phase and evaluate characterization of band and web formation on the edges of coronary stents.

Dye-staining cardioscopy enabled visualization of blood flow through the subendocardial microvessels or myocardial tissue fluid flow. This technique is useful for evaluation of the effects of coronary interventions or angiogenic therapy on coronary microcirculation.

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Authors and Affiliations

  1. Cardiovascular Center, Toho University Medical Center Sakura Hospital, Shimoshizu 564-1, Sakura, Chiba, 285-8741, Japan

    Takanobu Tomaru M.D., Ph.D.

  2. The Third Department of Internal Medicine, Teikyo University Chiba Medical Center, Anesaki 3426-3, Ichihara, Chiba, 299-0111, Japan

    Fumitaka Nakamura M.D.

  3. Department of Internal Medicine, Suwa Central Hospital, Suwa, Japan

    Yoshiharu Fujimori

  4. Public Trust Cardiovascular Fund, Shiba 3-33-1, Minato-Ku, Tokyo, 105-8574, Japan

    Yasumi Uchida M.D.

Authors
  1. Takanobu Tomaru M.D., Ph.D.
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  2. Fumitaka Nakamura M.D.
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  3. Yoshiharu Fujimori
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  4. Yasumi Uchida M.D.
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Corresponding author

Correspondence to Takanobu Tomaru M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Mitsukoshi Health and Welfare Foundation, Nippon Medical School, Tokyo, Japan

    Kyoichi Mizuno

  2. Cardiovascular Center, Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan

    Masamichi Takano

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© 2015 Springer Japan

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Tomaru, T., Nakamura, F., Fujimori, Y., Uchida, Y. (2015). Dye-Staining Coronary Angioscopy and Cardioscopy. In: Mizuno, K., Takano, M. (eds) Coronary Angioscopy. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55546-9_3

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  • DOI: https://doi.org/10.1007/978-4-431-55546-9_3

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-55545-2

  • Online ISBN: 978-4-431-55546-9

  • eBook Packages: MedicineMedicine (R0)

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