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ICG Fluorescent Image-Guided Surgery in Head and Neck Cancer

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ICG Fluorescence Imaging and Navigation Surgery

Abstract

Neck lymph node metastasis is the most significant prognostic factor of head and neck cancer; however, there remains debate as to the most effective treatment of clinical N0 neck metastasis. Sentinel lymph node (SLN) navigation surgery decreases morbidity associated with neck dissections and reduces the potential of recurrences. While radiocolloids have been previously used to detect SLN, disadvantages of radiocolloids are not only the lack of real-time intraoperative visual information but also the phenomena of “shine-through” radioactivity due to scattering from the primary site. This is especially problematic in cases of cancer located at the floor of the mouth. Additionally, radiocolloids may expose patients and medical staff to irradiation.

To negotiate these problems, ICG (indocyanine green) fluorescence imaging has been used for the detection of SLN, translymphatic chemotherapy, and intra-arterial chemotherapy in cases of head and neck cancer. The advantages of ICG fluorescence imaging include access to real-time intraoperative visual information and little affections of “shine through” even in cases of the floor of the mouth.

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Author information

Authors and Affiliations

  1. Department of Otolaryngology Head and Neck Surgery, Juntendo University, Tokyo, Japan

    Junkichi Yokoyama & Shinich Ohba

  2. Department of Otolaryngology Head and Neck Surgery, Moriyama Memorial Hospital, 7-12-7 Nishikasai, Edogawa-ku, Tokyo, 134-0088, Japan

    Junkichi Yokoyama

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  1. Junkichi Yokoyama
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  2. Shinich Ohba
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Correspondence to Junkichi Yokoyama .

Editor information

Editors and Affiliations

  1. Department of Surgery, Seiwa Memorial Hospital, Sapporo, Hokkaido, Japan

    Mitsuo Kusano

  2. Hepato-Biliary-Pancreatic Surgery Divisi, University of Tokyo, TOKYO 113-8655, Tokyo, Japan

    Norihiro Kokudo

  3. Department of Breast Surgery Graduate Sc, Kyoto University, Kyoto, Kyoto, Japan

    Masakazu Toi

  4. Department of Surgery, Hirakata Hospital, Kansai Medical University, Hirakata, Osaka, Japan

    Masaki Kaibori

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Yokoyama, J., Ohba, S. (2016). ICG Fluorescent Image-Guided Surgery in Head and Neck Cancer. In: Kusano, M., Kokudo, N., Toi, M., Kaibori, M. (eds) ICG Fluorescence Imaging and Navigation Surgery. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55528-5_5

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  • DOI: https://doi.org/10.1007/978-4-431-55528-5_5

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  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-55527-8

  • Online ISBN: 978-4-431-55528-5

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