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A New Concept for Axillary Treatment of Primary Breast Cancer Using Indocyanine Green Fluorescence Imaging

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ICG Fluorescence Imaging and Navigation Surgery

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Abstract

Sentinel lymph node (SLN) biopsy using fluorescence indocyanine green (fICG) method can visualize lymphatic vessels by real-time imaging and is technically straightforward. Identification and false-negative rates of SLN biopsy using fICG ranged from 93 to 100 % and 0 to 10 %, respectively, which were comparable to blue dye or radioisotope method. Four SLNs should be removed for the accurate staging of the axillary lymph node status. The fICG method seems to be advantageous for effective SLN dissection by the intraoperative visualization of a sentinel node bed. However, the number of SLNs removed can be adjusted by the risk of lymph node metastasis. SLN biopsy after preoperative systemic therapy (PST) in patients with clinical node positive is still challenging. There may be some advantage in fICG method for SLN detection after PST because the fICG method can identify an average of three SLNs. A prospective study to evaluate the accuracy of SLN identification using fICG after PST in node-positive patients is now warranted.

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Authors and Affiliations

  1. Department of Breast Surgery, Kyoto University Hospital, 54 Kawara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan

    Masahiro Takada

  2. Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

    Masakazu Toi

Authors
  1. Masahiro Takada
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  2. Masakazu Toi
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Correspondence to Masakazu Toi .

Editor information

Editors and Affiliations

  1. Department of Surgery, Seiwa Memorial Hospital, Sapporo, Hokkaido, Japan

    Mitsuo Kusano

  2. Hepato-Biliary-Pancreatic Surgery Divisi, University of Tokyo, TOKYO 113-8655, Tokyo, Japan

    Norihiro Kokudo

  3. Department of Breast Surgery Graduate Sc, Kyoto University, Kyoto, Kyoto, Japan

    Masakazu Toi

  4. Department of Surgery, Hirakata Hospital, Kansai Medical University, Hirakata, Osaka, Japan

    Masaki Kaibori

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© 2016 Springer Japan

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Takada, M., Toi, M. (2016). A New Concept for Axillary Treatment of Primary Breast Cancer Using Indocyanine Green Fluorescence Imaging. In: Kusano, M., Kokudo, N., Toi, M., Kaibori, M. (eds) ICG Fluorescence Imaging and Navigation Surgery. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55528-5_12

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  • DOI: https://doi.org/10.1007/978-4-431-55528-5_12

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  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-55527-8

  • Online ISBN: 978-4-431-55528-5

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