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CMOS-Based Neural Interface Device for Optogenetics

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Optogenetics
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Abstract

Optical and electronic neural interface devices based on complementary metal-oxide-semiconductor (CMOS) technology are presented. Concept, design strategy, and fabrication of the CMOS-based optoelectronic neural interface devices are described. Functional demonstrations of the devices are also presented.

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Acknowledgments

All the work presented in this article was achieved under collaboration with members of the Photonic Device Science Laboratory in the Graduate School of Materials Science, Nara Institute of Science and Technology. The optical stimulation experiment using ChR2-expressed cells was performed with great help from Professor Sadao Shiosaka and Assistant Professor Yasuyuki Ishikawa (currently with the Maebashi Institute of Technology) at the Graduate School of Bioscience, Nara Institute of Science and Technology.

This work was partly supported by the Japan Science and Technology Agency, Precursory Research for Embryonic Science and Technology (JST-PRESTO), Grant-in-Aid for Challenging Exploratory Research #50314539 from the Japan Society for the Promotion of Science, and the VLSI Design and Education Center (VDEC) at the University of Tokyo, in collaboration with Cadence Design Systems, Inc.

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Correspondence to Takashi Tokuda .

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Tokuda, T., Noda, T., Sasagawa, K., Ohta, J. (2015). CMOS-Based Neural Interface Device for Optogenetics. In: Yawo, H., Kandori, H., Koizumi, A. (eds) Optogenetics. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55516-2_27

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